Formulation and Evaluation of an Effervescent, Gastroretentive Drug-Delivery System - Pharmaceutical Technology

Latest Issue
PharmTech

Latest Issue
PharmTech Europe

Formulation and Evaluation of an Effervescent, Gastroretentive Drug-Delivery System
The authors developed a formulation for effervescent gastroretentive drug delivery techniques using ibuprofen as a model drug. They optimized the formulations by applying full factorial design.


Pharmaceutical Technology
Volume 10, Issue 34, pp. 60-71

References

1. L.F. Prescott and W.S. Nimmo, Novel Drug Delivery and Its Therapeutic Application, F.L. Prescott, Ed. (John Wiley and Sons, Oxford, UK, 1989), pp. 1–11.

2. Y.W. Chien, "Controlled and Modulated-Release Drug Delivery Systems," in Encyclopedia of Pharmaceutical Technology, J. Swarbrick and J.C. Boylan, Eds. (Marcel Dekker, New York, 1990), p. 280.

3. G. Chawla et al., Pharm. Technol. 27 (7), 50–68 (2003).

4. Medicines Complete, "Ibuprofen/Indomethacin," http://www.medicinescomplete.com/mc/martindale/current, accessed Dec. 19, 2006.

5. J.C. Valle-Jones, J. Smith, and D. Rowely-Jones, Br. J. Clin. Pract. 38 (7), 353–358 (1984).

6. T.H. Kantor, Ann. Intern. Med. 91 (6), 877–882 (1979).

7. A. Avgerinos and S. Malamataris, Int. J. Pharm. 63 (1), 77–80 (1990).

8. N. Sarkar et al., Curr. Ther. Res. Clin. Exp. 44 (6), 11–21 (1988).

9. M. Galeon et al., Curr. Ther. Res. Clin. Exp. 29 (4), 217–234 (1981).

10. S. Bolton and Charles Bon, "Factorial Designs," in Pharmaceutical Statistics: Practical and Clinical Applications, J. Swarbrick, Ed. (Marcel Dekker, New York, 3rd ed., 1984), pp. 265–285.

11. N.A. Armstrong and K.C. James, "Factorial Designs of Experiments," in Understanding Experimental Design and Interpretation in Pharmaceutics, (Ellis Harwood, London, 1990), pp. 27–54.

12. R. Ziyaur, A. Mushir, and R.K. Khar, Acta Pharm. 56 (2), 49–57 (2006).

13. N. Tomoya et al., Chem. Pharm. Bull. 54 (6), 14–51 (2006).

14. B.S. Dave, A.F. Amin, and M.M. Patel, AAPS PharmSciTech 5 (2), 45–49 (2004).

15. USP 27–NF 22 (USP, Rockville, MD, 2003), pp. 953–955.

16. M. Rosa, H. Zia, and T. Rhodes, Int. J. Pharm. 105 (34), 65–70 (1994).

17. G.S. Banker and N.R. Anderson, "Tablets," in The Theory and Practice of Industrial Pharmacy, L. Lachmann, H.A. Liberman, and J.L. Kaing, Eds. (Varghese Publishing House, Mumbai, 3rd ed., 1987), pp. 295–299.

18. "Tablets" (Indian Pharmacopoeia, (Controller of Publication, Delhi, India, Vol. II, 1996), pp. 734–736.

19. J. Castellanos, M.R.H. Zia, and C.T. Rhodes, Int. J. Pharm. 105 (34), (Apr25), 65–70 (1994).

20. J.E. Devereux, J.M. Newton, and M.B. Short, J. Pharm. Pharmacol. 42 (8), 500–501 (1990).

21. V.S. Chitnis, V.S. Malshe, and J.K. Lalla, Drug Dev. Ind. Pharm. 17 (10), 879–892 (1991).

22. G.M. Khan, Sciences 1 (8), 350–354 (2001).

23. D.M. Morkhade, Indian J. Pharm. Sci. 68 (3), 53–58 (2006).

24. T. Higuchi, J. Pharm. Sci. 52 (12), 1145–1149 (1963).

25. N.A. Peppas and J.J. Sahlin, Int. J. Pharm. 57 (1), 169–172 (1989).


ADVERTISEMENT

blog comments powered by Disqus
LCGC E-mail Newsletters

Subscribe: Click to learn more about the newsletter
| Weekly
| Monthly
|Monthly
| Weekly

Survey
How does your company apply quality-by-design (QbD) principles to manufacturing processes?
To all processes for both new and legacy products
To all process for new products only
To select process for new products only
To select processes for both new and legacy products
Do not use QbD
To all processes for both new and legacy products
20%
To all process for new products only
13%
To select process for new products only
24%
To select processes for both new and legacy products
20%
Do not use QbD
22%
View Results
UPCOMING CONFERENCES

Programs for Investigational and Pre-Launch Drugs
Philadelphia, PA
July 17-18, 2013
Request Brochure

Strategic Pipeline Planning & Portfolio Valuation
Philadelphia, PA
August 13-14, 2013
Request Brochure

MES 2013 - Forum on Manufacturing Execution Systems
Philadelphia, PA
August 14-15, 2013
Request Brochure

Mobile Innovation for the Life Sciences Industry
Philadelphia, PA
August 20-21, 2013
Request Brochure

See All Conferences >>

Eric Langer Outsourcing Outlook Eric LangerOutsourcing's Modest Role as a Cost-Containment Strategy
Patricia Van Arnum Ingredients Insider Patricia Van ArnumIntellectual Property Battles in Solid-State Chemistry
Nathan Jessop Industry Insider Nathan Jessop Campaign Against Counterfeit Drugs Continues
Lynn Torbeck Statistical Solutions Lynn D. TorbeckCompositing Samples and the Risk to Product Quality
 More
Inadequate Access to Medicines Puts EU at Risk
FDA Offers Insight on QbD for Modified-Release Products
Global Biosimilars Market to Reach $2.445 Billion in 2013
Adapting to Change
AstraZeneca and Exco InTouch Collaborate to Augment Current COPD Pathways
FindPharma Custom Search
Source: Pharmaceutical Technology,
Click here