Transdermal Delivery of Vaccines and Therapeutic Proteins - Pharmaceutical Technology

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PharmTech Europe

Transdermal Delivery of Vaccines and Therapeutic Proteins
The author reviews advances in technology that may soon allow transdermal delivery of two of the fastest growing drug classes on the pharmaceutical market. This article is part of a special Drug Delivery issue.


Pharmaceutical Technology
pp. s14-s20

41. K. J. Hansen et al., "Transdermal Delivery of Vaccines and Proteins using a Hand-Applied, Polymeric Microstructured Array," presented at the Controlled Release Society, Portland, OR, July 12, 2010.

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48. Q. Zhu et al., Proc. Natl. Acad. Sci. 106 (19), 7968–7973 (2009).

49. K. J. Hansen and B. Haldin, Drug Deliv. Technol. 8 (8), 38–42 (2008).

50 H. S. Gill, and M. R. Prausnitz, Jrnl. Control. Rel. 117 (2), 227–237 (2007).

51 P. E. Laurent et al., Vaccine 25 (52), 8833–8842 (2007).

52… I. Leroux-Roels et al., Vaccine 26 (51), 6614–6619 (2008).

53. J. Beran et al., BMC Med. 7 (13), (2009).

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56. S. A. Burton et al., Pharm. Res. (July 2010), http://www.springerlink.com/content/v33v3x4850877668/, accessed Oct. 13, 2010.

57. K. J. Hansen, S. A. Burton, and M. A. Tomai, Drug Deliv. Technol. 55 (8), 38–44 (2009).

58. K. J. Hansen, S. A. Burton, and T. A. Peterson, "Transdermal Delivery of Large Molecules through an Integrated Hollow Microneedle Device," presented at the Controlled release Society, Copenhagen, Denmark, July 2009.


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