Melt Extrusion: Shaping Drug Delivery in the 21st Century - Pharmaceutical Technology

Latest Issue
PharmTech

Latest Issue
PharmTech Europe

Melt Extrusion: Shaping Drug Delivery in the 21st Century
The authors provde a review of melt extrusion's evolution and applications in the pharmaceutical industry. This article is part of a special Drug Delivery issue.


Pharmaceutical Technology
pp. s30-s37

11. B. Elliott, "Film, Sheet and Laminates," in Pharmaceutical Extrusion Technology (I. Ghebre-Sellassie and C. Martin, Eds., Marcel Dekker, New York, 2003)p. 225 – 244.

12. B. Bessemer, "Shape Extrusion," in Pharmaceutical Extrusion Technology (I. Ghebre-Sellassie and C. Martin, Eds., Marcel Dekker, New York, 2003) pp. 209–224.

13. D.J. Hauss, Adv. Drug Deliv. Rev. 59 (7), 667–676 (2007).

14. K. Six et al., Pharm. Res. 20 (3), 1047–1054 (2003).

15. W. Curatolo, J.A. Nightingale, and S.M. Herbig, Pharm. Res. 26 (6), 1419–1431 (2009).

16. J.E. Patterson et al., Internat. Jrnl. of Pharmaceut. 336 (1) (2007).

17. J. C. DiNunzio, "Formulation Design of Melt Extruded Systems for Oral Bioavailability Enhancement" presented at Leistritz Pharmaceutical Extrusion Seminar, Clinton, NJ, 2010.

18. F. Zhang, "Hot-melt Extrusion as a Novel Technology to Prepare Sustained-Release Dosage Forms," in Division of Pharmaceutics (University of Texas at Austin, 1999) p. 259.

19. R. Spengler and J. Rosenberg, Methods of Produing Solid Dosing Forms (USPT Office, Ed., Abbott Laboratories, USA, 2003).

20. J.W. McGinity et al., "Hot-Melt Extrusion Technology," in Encyclopedia of Pharmaceutical Technology (J. Swarbrick, Ed., Informa Healthcare, New York, 2006).

21. W. Roth et al., Internat. Jour. of Pharmaceut. 368 (1–2), 72–75 (2009).

22. C. De Brabander et al., Internat. Journ. of Pharmaceut. 271 (1–2), 77–84 (2004).

23. S.U. Schilling and J.W. McGinity, Internat. Journ. of Pharmaceut. In-press (2010).

24. L.E. Appeal et al., Azithromycin Multiparticulate Dosage Forms by Melt-Congeal Processes (USPT Office, Ed., Pfizer, USA, 2004) p. 25.

25. J. Kowalski, et al., Internat. Journ. of Pharmaceut. 381 (1), 56–61 (2009).

26. W. De Graaff et al., Drug Delivery System Based on Polyethylene Vinylacetate Copolymers, (USPT Office, Ed., N.V. Organon, US, 2007) p. 14.

27. A. Loxley, "Hot Melt Extrusion in the Preparation of Anti-retroviral-releasing Intravaginal Rings" presented at Leistritz Pharmaceutical Extrusion Seminar, Clinton, NJ, 2010.

28. S. Jain et al., Indian Journ. of Pharmaceut. Sci. 69 (4), 562–567 (2007).

29. A. Rothen-Weinhold, Euro. Jrnl. of Pharmaceut. and Biopharmaceut. 49 (3), 253–257 (2000).


ADVERTISEMENT

blog comments powered by Disqus
LCGC E-mail Newsletters

Subscribe: Click to learn more about the newsletter
| Weekly
| Monthly
|Monthly
| Weekly

Survey
FDASIA was signed into law two years ago. Where has the most progress been made in implementation?
Reducing drug shortages
Breakthrough designations
Protecting the supply chain
Expedited reviews of drug submissions
More stakeholder involvement
Reducing drug shortages
33%
Breakthrough designations
11%
Protecting the supply chain
39%
Expedited reviews of drug submissions
11%
More stakeholder involvement
6%
View Results
Jim Miller Outsourcing Outlook Jim Miller Health Systems Raise the Bar on Reimbursing New Drugs
Cynthia Challener, PhD Ingredients Insider Cynthia ChallenerThe Mainstreaming of Continuous Flow API Synthesis
Jill Wechsler Regulatory Watch Jill Wechsler Industry Seeks Clearer Standards for Track and Trace
Siegfried Schmitt Ask the Expert Siegfried SchmittData Integrity
Sandoz Wins Biosimilar Filing Race
NIH Translational Research Partnership Yields Promising Therapy
Clusters set to benefit from improved funding climate but IP rights are even more critical
Supplier Audit Program Marks Progress
FDA, Drug Companies Struggle with Compassionate Use Requests
Source: Pharmaceutical Technology,
Click here