Exploring Excipient Functionality - Pharmaceutical Technology

Latest Issue

Latest Issue
PharmTech Europe

Exploring Excipient Functionality
This technical forum is part of a special issue on Solid Dosage and Excipients.

Pharmaceutical Technology
Volume 35, pp. s6-s11

Film coating section references

1. Z. Ayenew et al., Recent Patents on Drug Deliv. & Formul. 3 (1), 26–39 (2009).

2. BASF SE, Kollicoat Smartseal Technical Information (Ludwigshafen, Germany), Jan. 2011.

3. K. Kolter, F. Guth, and M. Angel, "Physiochemical Characteristics of a New Aqueous Polymer Designed for Taste-Masking and Moisture Protection," presented by BASF at AAPS Annual Meeting and Exposition, New Orleans, Nov, 14–18, 2010.

Formulation development and manufacturing

Despite the intensification of biologic-based drug development, solid dosage forms are the mainstay in the pharmaceutical industry. Changing regulatory requirements, increased cost pressures, and the need to innovate for better product life-cycle management and product differentiation, are leading pharmaceutical companies to seek ways to improve development and manufacturing.

Pharmaceutical Technology recently held an webcast to more fully examine the current and future direction in formulation development, dosage forms, and manufacturing of solid-dosage products, including the role of continuous processing and FDA's quality by design (QbD) initiative. Participating in the webcast, which was held Mar. 1, 2011, was Robin H. Bogner, R.Ph., Ph.D., associate professor of pharmaceutics in the Department of Pharmaceutical Science at the University of Connecticut, to discuss technical advances in solid-dosage formulations and dosage forms. John Groskoph, senior director of new products CMC, global chemistry manufacturing and controls at Pfizer, discussed QbD in solid-dosage manufacturing.

External development and manufacturing also are becoming more important in a pharmaceutical company's strategy. In another webcast, Pharmaceutical Technology examined how to optimize outsourcing CMC development and manufacturing. The webcast, which was broadcast on Mar. 8, 2011, featured Clive V. Bennett, nonexecutive chairman of Halo Pharmaceutical, Gregg Brandyberry, CEO of Wildfire Commerce and senior advisor of A.T. Kearney Procurement and Analytic Solutions, and former vice-president of procurement of global systems and operations at GlaxoSmithKline, and George Bobotas, PhD, and chief scientific officer at Halo Pharmaceutical. On-demand viewing on both webcasts are available in the multimedia section at http://PharmTech.com/.


blog comments powered by Disqus
LCGC E-mail Newsletters

Subscribe: Click to learn more about the newsletter
| Weekly
| Monthly
| Weekly

FDASIA was signed into law two years ago. Where has the most progress been made in implementation?
Reducing drug shortages
Breakthrough designations
Protecting the supply chain
Expedited reviews of drug submissions
More stakeholder involvement
Reducing drug shortages
Breakthrough designations
Protecting the supply chain
Expedited reviews of drug submissions
More stakeholder involvement
View Results
Eric Langerr Outsourcing Outlook Eric LangerTargeting Different Off-Shore Destinations
Cynthia Challener, PhD Ingredients Insider Cynthia ChallenerAsymmetric Synthesis Continues to Advance
Jill Wechsler Regulatory Watch Jill Wechsler Data Integrity Key to GMP Compliance
Sean Milmo European Regulatory WatchSean MilmoExtending the Scope of Pharmacovigilance Comes at a Price
From Generics to Supergenerics
CMOs and the Track-and-Trace Race: Are You Engaged Yet?
Ebola Outbreak Raises Ethical Issues
Better Comms Means a Fitter Future for Pharma, Part 2: Realizing the Benefits of Unified Communications
Better Comms Means a Fitter Future for Pharma, Part 1: Challenges and Changes
Source: Pharmaceutical Technology,
Click here