Pharmaceutical Excipients for Hot-Melt Extrusion - Pharmaceutical Technology

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Pharmaceutical Excipients for Hot-Melt Extrusion
The authors examine the influence of glass-transition temperature, melt viscosity, degredation temperature, and process settings.

Pharmaceutical Technology
Volume 35, Issue 5, pp. 74-82


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4. J.E. Patterson et al., Int. J. Pharm. 336 (1), 22–34 (2007).

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6. A. Forster et al., Int. J. Pharm. 226 (1–2), 147–161 (2001).

7. J.E. Patterson et al., Drug Dev. Ind. Pharm. 34 (1), 95–106 (2008).

8. S. Janssens et al., Eur. J. Pharm. Sci. 30 (3–4), 288–294 (2007).

9. S. Janssens and G. Van den Mooter, "Enhancing Solubility and Dissolution Rate of Poorly Soluble Drugs," WO 2007/115381, Oct. 2007.

10. E. Karavas et al., Eur. J. Pharm. Biopharm. 63 (2), 103–114 (2006).

11. R.J. Chokshi et al., J. Pharm Sci. 94 (11), 2463–2474 (2005).

12. S. Thumma et al., Eur. J. Pharm. Biopharm. 70 (2), 605–614 (2005).

Citation: When referring to this article, please cite it as "M.Karl, D. Djuric, K.Kolter, "Pharmaceutical Excipients for Hot-Melt Extrusion," Pharmaceutical Technology 35 (5) 74-82 (2011)."


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