Inhibiting the Precipitation of Poorly Water-Soluble Drugs from Labrasol Formulations - Pharmaceutical Technology

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Inhibiting the Precipitation of Poorly Water-Soluble Drugs from Labrasol Formulations
The study results suggested that Pluronic F127 might be a potent inhibitor of drug precipitation for Labrasol formulations.


Pharmaceutical Technology
Volume 35, Issue 6, pp. 50-54

References

1. R. Lipper, Modern Drug Discov. 2 (1), 255–260 (1999).

2. C.A. Lipinski, American Pharm. Rev. (Fall), 582–585 (2002).

3. C.A. Lipinski, J. Pharmacol. Toxicol. Methods 44 (1), 235–249 (2001).

4. R.A. Prentis, Y. Lis, and S.R. Walker, Br. J. Clin. Pharmacol. 25 (3), 387–396 (1988).

5. S.H. Yalkowsky, Solubility and Solubilization in Aqueous Media, S.H. Yalkowsky, Ed. (Oxford Univeristy Press, New York, 2000).

6. R.G. Strickley, Pharm. Res. 21 (2), 201–230 (2004).

7. P.C. Sheen et al., Int. J. Pharm. 118 (2), 221–227 (1995).

8. S. Fernandez et al., Pharm. Res. 26 (8), 1901–1910 (2009).

9. W.G. Dai, Int. J. Pharm. 393 (1–2), 1–16 (2010).

10. W.G. Dai et al., J. Pharm. Sci. 96 (11), 2957–2969 (2007).

11. B.A. Hoener and L.Z. Benet, "Factors Influencing Drug Absorption and Drug Availability," in Drugs and the Pharmaceutical Sciences, G.S. Banker and C. Rhodes, Eds. (Informa Healthcare, New York, 4th ed., 2002), pp. 93–117.

12. S. Barakat Nahla, J. Pharm. Pharmacol. 62 (2), 173–180 (2010).

13. T.R. Kommuru et al., Int. J. Pharm. 212 (2), 233–246 (2001).

14. H.J. Kim et al, Drug Dev. Ind. Pharm. 26 (5), 523–529 (2000).

15. G. Venkatesh et al., Drug Dev. Ind. Pharm. 36 (6), 735–745 (2010).

16. W.G. Dai et al., Int. J. Pharm. 336 (1), 1–11 (2007).

17. W.G. Dai et al., Adv. Drug Deliv. Rev. 60 (6), 657–672 (2008).

18. A.R. Das et al., J. Surf. Sci. Technol. 14 (1–4), 41–47 (1998).

19. M.G. Neumann, C.C. Schmitt, and E.T. Iamazaki, Carbohydr. Res. 338 (10), 1109–1113 (2003).

20. T. Yoshimura, A. Ohno, and K. Esumi, J. Colloid Interface Sci. 272 (1), 191–196 (2004).

21. V.A.d.O. Tiera, M.J. Tiera, and M.G. Neumann, J. Dispers. Sci. Technol. 22 (2 & 3), 177–184 (2001).

22. M.S. Bakshi et al., J. Colloid Interface Sci. 286 (1), 369–377 (2005).

23. P.A. Bhat, G.M. Rather, and A.A. Dar, J. Phys. Chem. B 113 (4), 997–1006 (2009).

24. L.S.C. Wan and P.F.S. Lee, Can. J. Pharm. Sci. 10 (3), 69–73 (1975).

25. M.S. Bakshi and K. Singh, J. Colloid Interface Sci. 287 (1), 288–297 (2005).

26. M.S. Bakshi et al., Colloids Surf. A Physicochem. Eng. Asp. 278 (1–3), 129–139 (2006).

27. W.G. Dai et al., Int. J. Pharm. 355 (1–2), 31–37 (2008).

Citation: When referring to this article, please cite it as "W.G. Dai, L.C. Dong, and A.A. Creasey, "Inhibiting the Precipitation of Poorly Water Soluble Drugs from Labrasol Formulations," Pharmaceutical Technology 35 (6) 50-54(2011)."


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