Conclusion
The authors described a method for controlled release of therapeutics from porous materials that has the potential to be applied
to various therapeutics and types of porous materials. The method involves the application of a plasma-polymer layer on top
of porous materials, and the thickness of this layer controls release kinetics. Athough the current study emphasizes plasma
polymerization as a tool to reduce pore diameter at the surface, future work should consider the influence of the plasma polymer's
physical properties, such as hydrophilicity, on drug release. The ability of plasma polymerization to provide films of various
physical and chemical properties provides enormous flexibility for fine tuning drug-release platforms to suit various drugs
and applications.
Spomenka Simovic is a doctor of colloid chemistry and pharmaceutics, Dusan Losic is associate professor of nanostructured materials, and Krasimir Vasilev* is an Australian Future fellow, all at the University of South Australia, Mawson Lakes Campus, 5095 Mawson Lakes, South Australia,
fax: +61 8 830 25689, krasimir.vasilev@unisa.edu.au
.
*To whom all correspondence should be addressed.
Submitted: Feb. 17, 2011. Accepted: May 13, 2011
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Citation: When referring to this article, please cite it as "S. Simovic; D. Losic; K. Vasilev, "Controlled Release from Porous
Platforms," Pharmaceutical Technology 35 (8) 68-71(2011)."
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