The pharmaceutical majors manufacturing activities in 2010 and 2011 to date have been marked by several common themes: ongoing
restructuring and select investment in biologic-based manufacturing, particularly vaccines, and emerging markets. China and
India continue to be targets of investment, particularly through alliances or joint ventures, and investments are being made
in Russia and Brazil as well.
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Pfizer is continuing a restructuring of its manufacturing network, which was announced in May 2010, as part of its integration
plan following its $68-billion acquisition of Wyeth in 2009. As of Dec. 31, 2010, Pfizer operated plants in 76 locations on
a global basis with major manufacturing facilities in Belgium, China, Germany, Ireland, Italy, Japan, the Philippines, Puerto
Rico, Singapore, and the continental United States. The company's plant network strategy calls for the exit of nine sites
during the next several years, according to the company's 2010 annual filing with the US Securities and Exchange Commission
Pfizer's strategy, as detailed in May 2010, includes plans to discontinue operations at three solid-dosage sites in Caguas,
Puerto Rico; Loughbeg, Ireland; and Rouses Point, New York. Pfizer also announced plans to phase out pharmaceutical solid-dosage
manufacturing in Guayama, Puerto Rico, but that site will expand its consumer-healthcare operations. Reductions are planned
at two other solid-dosage facilities in Illertissen, Germany, and Newbridge, Ireland.
Table I: Top 50 pharmaceutical companies (Rankings 1–25).
Two aseptic facilities that make sterile injectable medicines were targeted for exit: Dublin, Ireland, and Carolina, Puerto
Rico. Pfizer also announced changes to its biopharmaceutical-manufacturing network. The company said it planned to exit operations
in Shanbally, Ireland, and Pearl River, New York. The Pearl River site, however, will remain Pfizer's center of excellence
for vaccine research and development (R&D). Biotechnology plants in Sanford, North Carolina, Andover, Massachusetts, and Havant,
United Kingdom, are expected to see reductions.
Table II: Top 50 pharmaceutical companies (Rankings 26–50).
Pfizer reported plans to cease production of consumer-healthcare products at its plant in Richmond, Virginia, but consumer
healthcare R&D operations will continue in Richmond. The timing of specific exits will depend upon the complexity of operations,
the amount of time needed for product transfers, and other business requirements, said Pfizer in a May 2010 press release.