GlaxoSmithKline. GlaxoSmithKline (GSK) is moving ahead with a global restructuring program that is on track to deliver a target of £2.2 billion ($3.6 billion) of annual savings by 2012. These savings have been extracted from GSK's developed-country sales and marketing structure, support functions, R&D, and manufacturing infrastructure. Along with these changes are increased investment in emerging markets, according to the company's 2010 annual filing.

In emerging markets, in June 2011, GSK agreed to acquire Shenzhen Neptunus Interlong Bio-Technique's stake in the companies' previously formed joint venture, Shenzhen GSK–Neptunus Biologicals, for $39 million. The joint venture develops and manufactures seasonal and pandemic influenza vaccines in China, Hong Kong, and Macau. In December 2010, GSK agreed to acquire the Chinese pharmaceutical company, Nanjing MeiRui Pharma, including a manufacturing facility in Nanjing City, Jiangsu Province, China. In Russia, GSK formed an alliance with JSC Binnopharm for the local secondary manufacture of several GSK vaccines. Under this alliance, which was announced in November 2010, GSK will supply bulk vaccine and provide technology and expertise to enable Binnopharm to undertake the secondary manufacture, including filling and packaging of GSK vaccines. Binnopharm will be responsible for gaining approval of their facilities to allow supply of GSK cervical cancer, rotavirus, and pneumococcal vaccines under Binnopharm's trademark for the Russian public market.

In biologics, in September 2010, GSK and the Swiss custom manufacturing organization Lonza formed an agreement under which Lonza will supply manufacturing capacity for five GSK early-stage monoclonal antibodies. Lonza will initially manufacture clinical-trial batches of five compounds currently in Phase I and II development and provide flexible capacity for late-stage development and commercial launch. As part of the agreement, GSK will work with Lonza to assess options for the design, specification, location, and construction of a biopharmaceutical manufacturing facility within the United Kingdom.