Inhaled Product Characterization - Pharmaceutical Technology

Latest Issue
PharmTech

Latest Issue
PharmTech Europe

Inhaled Product Characterization
The authors discuss the analysis of the resulting data, focusing on methods for the calculation of mass median ærodynamic diameter, one of the metrics routinely used for comparative testing.


Pharmaceutical Technology
pp. s33-s37

References

1. Stimuli to the Revision Process, "Generalized Simplified Approaches for Mass Median Aerodynamic Determination," Pharmacopeial Forum 36 (3) (2010).

2. M. Copley and J. McDonald, Inhalation 3 (11), 14–17 (2009)

3. W.C. Hinds, Aerosol Technology, Properties, Behavior, and Measurement of Airborne Particles (John Wiley & Sons, 2nd ed., 1999).

4. T.K. Church et al., Proc. Respiratory Drug Deliv. XII, 2, 509–509–512 (2010).

5. D.J. Finney, Probit Analysis (Cambridge University Press, Cambridge, 1971).

6. USP 34–NF 29, Physical Tests and Determinations <601> "Aerosols, Nasal Sprays, Metered-dose Inhalers, and Dry Powder Inhalers," pp. 237–239.

7. D. Lewis, Inhalation (August 2008).

8. Inhalation Report, "How do you calculate MMAD," (2010), http://www.inhalationreport.com/, accessed 10 Oct. 2011.

9. Tougas et al., AAPS Pharm. Sci. Technol., 10 (4) 1276–1285 (2009)

10. Proceedings of EPAG AIM Workshop at DDL 21 (Edinburgh International Conference Center, Dec. 8–10, 2010).

11. P.N. Pantelides et al., proceedings of RDD Europe (Berlin, 2011), pp. 391–395.


ADVERTISEMENT

blog comments powered by Disqus
LCGC E-mail Newsletters

Subscribe: Click to learn more about the newsletter
| Weekly
| Monthly
|Monthly
| Weekly

Survey
FDASIA was signed into law two years ago. Where has the most progress been made in implementation?
Reducing drug shortages
Breakthrough designations
Protecting the supply chain
Expedited reviews of drug submissions
More stakeholder involvement
Reducing drug shortages
38%
Breakthrough designations
13%
Protecting the supply chain
38%
Expedited reviews of drug submissions
13%
More stakeholder involvement
0%
View Results
Jim Miller Outsourcing Outlook Jim Miller Health Systems Raise the Bar on Reimbursing New Drugs
Cynthia Challener, PhD Ingredients Insider Cynthia ChallenerThe Mainstreaming of Continuous Flow API Synthesis
Jill Wechsler Regulatory Watch Jill Wechsler Industry Seeks Clearer Standards for Track and Trace
Siegfried Schmitt Ask the Expert Siegfried SchmittData Integrity
NIH Translational Research Partnership Yields Promising Therapy
Clusters set to benefit from improved funding climate but IP rights are even more critical
Supplier Audit Program Marks Progress
FDA, Drug Companies Struggle with Compassionate Use Requests
USP Faces New Challenges
Source: Pharmaceutical Technology,
Click here