Applying Quality by Design for Extended Release Hydrophilic Matrix Tablets - Pharmaceutical Technology

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Applying Quality by Design for Extended Release Hydrophilic Matrix Tablets
This study examines the effect and interaction of variations in hypromellose physicochemical properties.


Pharmaceutical Technology
Volume 36, Issue 10, pp. 106-116

References

1. L.X. Yu, Pharm. Res. 25(4), 781–791 (2008).

2. T.D. Cabelka et al., "Application of Quality by Design Principles to the Formulation of aHydrophilic Matrix Tablet of a High Dose/High Solubility Drug," presented at the AAPS Annual Meeting (Los Angeles, 2009).

3. T.D Cabelka et al., "Application of Quality by Design Principles to the Formulation of Extended-Release Propranolol Hydrochloride Hydrophilic Matrix Tablets," presented at the AAPS Annual Meeting (New Orleans, 2010).

4. H. Deng et al., "Application of Quality by Design Principles to the Formulation of Extended-Release Theophylline Hydrophilic Matrix Tablets," presented at the CRS Annual Meeting and Exposition (National Harbor, Maryland, 2011).

5. A.S. Rathore and H. Winkle, Nature Biotechnol. 27 (1) 26–34 (2009).

6. ICH, ICH Q8(R2) Pharmaceutical Development (2009).

7. USP 30–NF 25, "USP Monographs: Hypromellose," online, http://www.uspnf.com/, accessed May 10, 2008.

8. J.E. Hogan, Drug Dev. Ind. Pharm. 15 (6), 975–1999 (1989).

9. P. Gao et al., J. Pharm. Sci. 85 (7), 732–740 (1996).

10. M. Levina and A.R. Rajabi-Siahboomi, J. Pharm. Sci. 93 (11), 2746–2754 (2004).

11. K. Mitchell et al., Int. J. Pharm. 66 (1–3), 233–242 (1990).

12. A.R. Rajabi-Siahboomi, A. Nokhodchi, and M.H. Rubinstein, "Compaction Behavior of Hydrophilic Cellulose Ether Polymers," in Pharm. Technol. Yearbook: Tableting and Granulation (1998), pp. 32–40 .

13. R.W. Korsmeyer et al., Int. J. Pharm. 15 (1), 25–35 (1983).


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