Gaining Stereoselectivity in Asymmetric Synthesis - Pharmaceutical Technology

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Gaining Stereoselectivity in Asymmetric Synthesis
Researchers use inorganic catalysts as an alternative to biocatalysts in the selective conversion of sugars to produce chiral building blocks.


Pharmaceutical Technology
Volume 37, Issue 2

References

1. Y. Román-Leshkov, "Sn-Beta Zeolites with Borate Salts Catalyze the Epimerization of Carbohydrates via an Intramolecular Carbon Shift," Nature Comnun., online, DOI:10.1038/ncomms2122, Oct. 9, 2012.

2. I. Shiina, J. Med Chem. 56 (1), 150–159 (2013).

3. J. Zhou, "Organocatalytic Asymmetric Synthesis of 3,3-Disubstituted Oxindoles Featuring Two Heteroatoms at C3 position," Chem. Commun., online, DOI: 10.1039/C3CC38819K, Jan. 23, 2013.

4. A.D. Lim, J.A. Codelli, and S.E. Reisman, "Catalytic Asymmetric Synthesis of Highly Substituted Pyrrolizidines," Chem. Sci., online, DOI: 10.1039/C2SC21617E, Nov. 13, 2012.

5. M.J. Abrahamson, Angew. Chem., Int. Ed. Engl., 51 (16), 3969–3972 (2012).

6. G. Sahoo, Angew. Chem., Int. Ed. Engl. 51 (52), 13144–13148 (2012).

7. W. Sommer and D. Weibel, Aldrich ChemFiles 8.2 (56) (2008).

8. D.H. Paull, J. Am. Chem. Soc., 134 (27), 11128–11131 (2012).

9. C. Drahl, Chem. & Eng. News 90 (28), 29 (2012).

Patricia Van Arnum is executive editor of Pharmaceutical Technology, 485 Route One South, Bldg F, First Floor, Iselin, NJ 08830 tel. 732.346.3072,
twitter@PharmTechVArnum


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