Continuous Improvement in Tablet Coating and Dry Granulation - Pharmaceutical Technology

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Continuous Improvement in Tablet Coating and Dry Granulation
Recent advances in equipment design and operation in spraying, drying, and mixing can improve the tablet-coating process.

Pharmaceutical Technology
pp. s12-s16


This study proves the functionality of the new roller compactors. It was possible to precisely produce a representative placebo granule formulation with negligible material waste during process start-up. Furthermore, the study shows that a suitable sieve setup offers the possibility to achieve a desired granule size by altering screen size and sieve speed.


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5. P. Kleinebudde, Eur. J. Pharm. Biopharm. 58 (2), 317-326 (2004).

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Martin Hack* is vice-president and general manager, and Dejan Djuric, PhD, is manager of scientific operations, both at L.B. Bohle, 700 Veterans Circle, Suite 100, Warminster, PA 18974, tel. 215.957.1240,

* To whom all correspondence should be addressed.


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