This study proves the functionality of the new roller compactors. It was possible to precisely produce a representative placebo
granule formulation with negligible material waste during process start-up. Furthermore, the study shows that a suitable sieve
setup offers the possibility to achieve a desired granule size by altering screen size and sieve speed.
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Martin Hack* is vice-president and general manager, and Dejan Djuric, PhD, is manager of scientific operations, both at L.B. Bohle, 700 Veterans Circle, Suite 100, Warminster, PA 18974, tel.
* To whom all correspondence should be addressed.