Articles by Arvind K. Bansal - Pharmaceutical Technology

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Articles by Arvind K. Bansal

Variables Affecting Reconstitution Time of Dry Powder for Injection

The authors describe the factors affecting reconstitution time of dry powder for injection and classifies them as intrinsic and extrinsic parameters.
Jul 2, 2008

The authors describe the factors affecting reconstitution time of dry powder for injection and classifies them as intrinsic and extrinsic parameters.

Salt Selection in Drug Development

The selection of an appropriate salt form for a potential drug candidate is an opportunity to modulate its characteristics to improve bioavailability, stability, manufacturability, and patient compliance.
Mar 2, 2008

The selection of an appropriate salt form for a potential drug candidate is an opportunity to modulate its characteristics to improve bioavailability, stability, manufacturability, and patient compliance.

Formulation Development for Sterile Liquid Products in Blow–Fill–Seal Packs

Oct 2, 2006

Plastic has emerged gradually as a viable packaging material, even for sterile products. Acceptance of plastics has been encouraged by blow–fill–seal (BFS) technology, which provides scientific and commercial benefits. BFS technology has, however, brought new challenges for formulation-development scientists. This article highlights the specific concerns for the development of sterile liquid products and the formulation strategies to address these concerns.

The Role of Reverse Engineering in the Development of Generic Formulations

The authors propose a decision-tree approach for reverse engineering an innovator tablet formulation to quickly and effectively develop a generic formulation
Aug 2, 2005

Being the first to gain the most is a fundamental principle in the generics business because several companies compete to create generics of successful products going off patent. For a generics company to maintain revenue growth in a market in which product prices continue to fall, it must secure a continuous flow of new products, with quality and speed to market being key drivers. Thus, generics companies must be highly skilled in product and process development (1), the generics business, and achieving bioequivalence—the most critical development area.

Coprocessed Excipients for Solid Dosage Forms

Jan 2, 2004

The authors examine the development and performance of coprocessed excipients, including testing them for flowability, compressibility, amd dilution potential.

Gastrorentention: A Means to Address REgional Variability in Intestinal Drug Absorption

Jul 2, 2003

The bioavailability and absorption of orally administered drugs can be improved by prolonging gastroretention through the use of floating, swelling, bioadhesive, or high-density systems.

Product Development Issues of Powders for Injection

Mar 1, 2002

The development of a successful powder for injection formulation requires careful study of preformulation parameters, packaging and process parameters, and the elimination of particulate matter.

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