Articles by Harry G. Brittain, PhD - Pharmaceutical Technology

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Articles by Harry G. Brittain, PhD

The Path to Product Stability Is through Water

Readers can learn about the importance of measuring and controlling water activity in a comprehensive new book.
Dec 2, 2009
By: Harry G. Brittain, PhD

Readers can learn about the importance of measuring and controlling water activity in a comprehensive new book.

Strategy for the Prediction and Selection of Drug Substance Salt Forms

Through consideration of the ionic equilibria of acids and bases, one may readily calculate the formation constant of a salt species solely on the basis of knowledge of the pKA value of the acid and the pKB value of the base.
Oct 2, 2007
By: Harry G. Brittain, PhD

Through consideration of the ionic equilibria of acids and bases, one may readily calculate the formation constant of a salt species solely on the basis of knowledge of the pKA value of the acid and the pKB value of the base.

Determination by Analytical Sieving: Particle-Size Distribution, Part III

Dec 2, 2002
By: Harry G. Brittain, PhD

The author discusses the use of analytical sieving to determine the size distribution of granular and course powders and describes proper sieve construction and USP General Test {786}.

Particle-Size Distribution II: The Problem of Sampling Powdered Solids

Jul 1, 2002
By: Harry G. Brittain, PhD

Dynamic powder-sampling methods may be the best techniques for obtaining a representative sample for determining particle-size distribution.

What Is the "Correct" Method to Use for Particle-Size Determination?

Jul 1, 2001
By: Harry G. Brittain, PhD

Appropriate sampling procedures, proper preparation, and correct instrumental parameters may yield differing, but correct, results.

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