Articles by Adeline Siew, PhD - Pharmaceutical Technology

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Articles by Adeline Siew, PhD

New Technology Enables Integrated Chromatographic Separation and Mass Detection

Mass detection at the push of a button could change the way many laboratories carry out their chromatographic analysis.
Oct 23, 2013

Mass detection at the push of a button could change the way many laboratories carry out their chromatographic analysis.

Solving the Insoluble

Oct 23, 2013

PharmTech spoke with Dow about innovations in polymers to address poor solubility.

Unlocking the True Potential of Antibody Drug Conjugates

The success of Adcetris and Kadcyla is paving the way for more antibody drug conjugates to enter the market, especially in the treatment of solid tumors.
Oct 18, 2013

The success of Adcetris and Kadcyla is paving the way for more antibody drug conjugates to enter the market, especially in the treatment of solid tumors.

Ethyl cellulose aqueous dispersion: a coating system for oral sustained-release dosage forms

Formulation and process considerations for ethyl cellulose aqueous dispersion in sustained-release applications.
Oct 7, 2013

Formulation and process considerations for ethyl cellulose aqueous dispersion in sustained-release applications.

Elucidating Biosimilars Characterization

Industry experts discuss the importance of characterization studies during biosimilars development and related analytical methods.
Oct 2, 2013

Industry experts discuss the importance of characterization studies during biosimilars development and related analytical methods.

Evaluating Strategies for Oral Absorption Enhancement

Formulation scientists tackle the challenges of improving drug absorption across the gastrointestinal membrane.
Oct 2, 2013

Scientists from the CDMO Metrics talk about the challenges in developing oral formulations for poorly permeable drugs and the strategies used to enhance oral absorption in the gastrointestinal tract.

Novel Solvent-Free Method to Manufacture Metastable Drug Forms

Researchers from the University of Bradford, UK, have developed a solvent-free, continuous method to manufacture the more soluble and bioavailable form of artemisinin. The metastable form produced using high-temperature extrusion has been shown to have greater stability and longer shelf-life.
Sep 30, 2013

Researchers from the University of Bradford, UK, have developed a solvent-free, continuous method to manufacture the more soluble and bioavailable form of artemisinin. The metastable form produced using high-temperature extrusion has been shown to have greater stability and longer shelf-life.

Roche's Timesaving Formulation for Breast Cancer Drug Approved in Europe

The new subcutaneous formulation of Herceptin can be administered six times faster than the standard intravenous formulation.
Sep 2, 2013

The new subcutaneous formulation of Herceptin can be administered six times faster than the standard intravenous formulation.

Novartis' MS Drug Gilenya Under FDA Investigation for PML Case

FDA has issued a safety alert after a patient with multiple sclerosis (MS) in Europe developed a rare and serious brain infection known as progressive multifocal leukoencephalopathy (PML) following treatment with Gilenya (fingolimod).
Sep 2, 2013

FDA has issued a safety alert after a patient with multiple sclerosis in Europe developed a rare and serious brain infection known as progressive multifocal leukoencephalopathy following treatment with Gilenya (fingolimod).

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