Articles by Adeline Siew, PhD - Pharmaceutical Technology

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Articles by Adeline Siew, PhD

Solving the Insoluble

Oct 23, 2013

PharmTech spoke with Dow about innovations in polymers to address poor solubility.

Science-Based Technical Report Being Developed to Ensure Effective Use of Blow-Fill-Seal Technology

The Parenteral Drug Association has established a task force to develop a peer- and regulatory agency-reviewed Technical Report that will serve as a science-based industry reference document.
Oct 23, 2013

The Parenteral Drug Association has established a task force to develop a peer- and regulatory agency-reviewed Technical Report that will serve as a science-based industry reference document.

Unlocking the True Potential of Antibody Drug Conjugates

The success of Adcetris and Kadcyla is paving the way for more antibody drug conjugates to enter the market, especially in the treatment of solid tumors.
Oct 18, 2013

The success of Adcetris and Kadcyla is paving the way for more antibody drug conjugates to enter the market, especially in the treatment of solid tumors.

Ethyl cellulose aqueous dispersion: a coating system for oral sustained-release dosage forms

Formulation and process considerations for ethyl cellulose aqueous dispersion in sustained-release applications.
Oct 7, 2013

Formulation and process considerations for ethyl cellulose aqueous dispersion in sustained-release applications.

Elucidating Biosimilars Characterization

Industry experts discuss the importance of characterization studies during biosimilars development and related analytical methods.
Oct 2, 2013

Industry experts discuss the importance of characterization studies during biosimilars development and related analytical methods.

Evaluating Strategies for Oral Absorption Enhancement

Formulation scientists tackle the challenges of improving drug absorption across the gastrointestinal membrane.
Oct 2, 2013

Scientists from the CDMO Metrics talk about the challenges in developing oral formulations for poorly permeable drugs and the strategies used to enhance oral absorption in the gastrointestinal tract.

Novel Solvent-Free Method to Manufacture Metastable Drug Forms

Researchers from the University of Bradford, UK, have developed a solvent-free, continuous method to manufacture the more soluble and bioavailable form of artemisinin. The metastable form produced using high-temperature extrusion has been shown to have greater stability and longer shelf-life.
Sep 30, 2013

Researchers from the University of Bradford, UK, have developed a solvent-free, continuous method to manufacture the more soluble and bioavailable form of artemisinin. The metastable form produced using high-temperature extrusion has been shown to have greater stability and longer shelf-life.

Novartis' MS Drug Gilenya Under FDA Investigation for PML Case

FDA has issued a safety alert after a patient with multiple sclerosis (MS) in Europe developed a rare and serious brain infection known as progressive multifocal leukoencephalopathy (PML) following treatment with Gilenya (fingolimod).
Sep 2, 2013

FDA has issued a safety alert after a patient with multiple sclerosis in Europe developed a rare and serious brain infection known as progressive multifocal leukoencephalopathy following treatment with Gilenya (fingolimod).

Gauging the Outlook of the Biologics Market

A Q&A with Mike Jenkins, Catalent
Sep 2, 2013

Mike Jenkins, general manager of Catalent Biologics discusses the evolving landscape of the biologics market and hurdles faced in the development and manufacture of these innovative products.

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