Articles by Cynthia Challener, PhD - Pharmaceutical Technology

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Articles by Cynthia Challener, PhD

The Mainstreaming of Continuous Flow API Synthesis

The pharma industry is moving toward commercial-scale continuous processes for small-molecule API manufacturing.
Jul 2, 2014

The pharma industry is moving toward commercial-scale continuous processes for small-molecule API manufacturing.

Advances in Real-Time Bioreactor Sampling

The Modular Automated Sampling Technology platform takes online samples from bioreactors and transfers them directly to analytical devices.
Jun 18, 2014

The Modular Automated Sampling Technology platform takes online samples from bioreactors and transfers them directly to analytical devices.

Alternatives to Precious Metal Catalysts Sought

Industry seeks alternatives to costly and toxic precious metals used to form the catalysts for organic synthesis.
Jun 2, 2014

Industry seeks alternatives to costly and toxic precious metals used to form the catalysts for organic synthesis.

Seeking Alternative Catalyst Solutions

Transition metal-containing catalysts are widely used in organic synthesis, but many are based on expensive, rare metals. Researchers are seeking more sustainable alternatives.
Jun 2, 2014

Transition metal-containing catalysts are widely used in organic synthesis, but many are based on expensive, rare metals. Researchers are seeking more sustainable alternatives.

Cocrystals: Industry Takes a Wait-and-See Approach

The perceived risks associated with cocrystals may be slowing progress of their industrial application.
May 30, 2014

The perceived risks associated with cocrystals may be slowing progress of their industrial application.

HPAPIs: Fast-growing Segment Presents Challenges and Opportunities

Appropriate process design and engineering are critical for the production of small-molecule and biologic HPAPIs.
May 30, 2014

Appropriate process design and engineering are critical for the production of small-molecule and biologic HPAPIs.

Scientific Advances in Cocrystals are Offset by Regulatory Uncertainty

Drug developers are taking a wait-and-see approach to the use of cocrystals.
May 2, 2014

Drug developers are taking a wait-and-see approach to the use of cocrystals.

Packaging Becomes Enabler for Biopharmaceuticals

May 2, 2014

Once an afterthought, packaging has now become an essential component of biopharmaceutical product development and marketing.

Process Design Is Critical for Commercial Manufacture of HPAPIs

Increasing potency and growing interest in antibody-drug conjugates are creating challenges for manufacturers of HPAPIs.
May 2, 2014

Increasing potency and growing interest in antibody-drug conjugates are creating challenges for manufacturers of HPAPIs.

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Jim Miller Outsourcing Outlook Jim MillerOutside Looking In
Cynthia Challener, PhD Ingredients Insider Cynthia ChallenerAdvances in Large-Scale Heterocyclic Synthesis
Jill Wechsler Regulatory Watch Jill Wechsler New Era for Generic Drugs
Sean Milmo European Regulatory WatchSean MilmoTackling Drug Shortages
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