Articles by Patricia Van Arnum - Pharmaceutical Technology

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Articles by Patricia Van Arnum

Overcoming Challenges in Fluorine-Based Chemistry

Fluorinated molecules are important as pharmaceutical compounds. Recent advances involve selective and late-stage insertion of fluorine into small molecules.
Oct 2, 2013

Fluorinated molecules play an important role as pharmaceutical compounds. Recent advances seek to overcome the challenges of selective and late-stage insertion of fluorine into small molecules.

AstraZeneca, Bristol-Myers Squibb Recall Certain Lots of Bydureon

Sep 24, 2013

AstraZeneca, Bristol-Myers Squibb recall certain lots of of their antidiabetes drug Bydureon (eventide) due to manufacturing records that batches may contain underfilled vials.

Amgen’s Acqusition of Onyx Leads Biopharmaceutical Dealmaking in 2013

Mergers and acquisition activity on both a volume and value basis is up thus far in 2013 comparative to 2012.
Sep 4, 2013

Mergers and acquisition activity on both a volume and value basis is up thus far in 2013 comparative to 2012.

CROs Face Issues with Talent Retention

A recent survey shows that talent retention is an issue on industry level for contract research organizations (CROs), particularly for CROs located outside the United States.
Sep 4, 2013

A recent survey shows that talent retention is an issue on industry level for contract research organizations (CROs), particularly for CROs located outside the United States.

Advancing Chiral Chemistry in Pharmaceutical Synthesis

Sep 2, 2013

Developments involve stereoretentive cross-coupling, enantioselective alcohol silylation, strategies for amplifying signals in circular dichroism spectroscopy, and a synthetic route for the natural product ingenol.

Quality by Design in APIs

The adoption of quality by design in small-molecule drug development and manufacturing continues to evolve as the industry seeks ways to augment process understanding for APIs
Sep 2, 2013

The adoption of quality by design in small-molecule drug development and manufacturing continues to evolve as the industry seeks ways to augment process understanding for APIs

Risk Assessment of Excipients

Sep 1, 2013

Industry experts share perspectives on risk assessment and mitigation in excipient manufacture and the excipient supply chain.

Gaining Insights on Contract Chemical API Manufacturing

Industry experts share their views on the outsourcing model and the current and future direction of contract chemical API manufacturing.
Sep 1, 2013

Industry experts share their views on the outsourcing model and the current and future direction of contract chemical API manufacturing.

Siegfried Proceeds with Expansion in China and Switzerland

Aug 27, 2013

Siegfried is proceeding with its expansion in China and Switzerland.

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Jim Miller Outsourcing Outlook Jim MillerCMO Industry Thins Out
Cynthia Challener, PhD Ingredients Insider Cynthia ChallenerFluorination Remains Key Challenge in API Synthesis
Marilyn E. Morris Guest EditorialMarilyn E. MorrisBolstering Graduate Education and Research Programs
Jill Wechsler Regulatory Watch Jill Wechsler Biopharma Manufacturers Respond to Ebola Crisis
Sean Milmo European Regulatory WatchSean MilmoHarmonizing Marketing Approval of Generic Drugs in Europe
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