Articles by Adeline Siew, PhD - Pharmaceutical Technology

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Articles by Adeline Siew, PhD

Industry Perspectives: Achieving Solutions for the Challenge of Poorly Water-Soluble Drugs

A multifaceted approach is needed to resolve the myriad of challenges in developing oral formulations of poorly soluble drugs.
Jun 2, 2013

A multifaceted approach is needed to resolve the myriad of challenges in developing oral formulations of poorly soluble drugs.

Amgen and Astellas Form Joint Venture to Address Unmet Medical Needs in Japan

May 29, 2013

Amgen and Astellas have entered into a strategic alliance to provide new medicines for serious unmet medical needs of Japanese patients. The alliance leverages the complementary capabilities of both companies through an innovative business model that combines Amgen's pipeline candidates with Astellas' deep knowledge of Japanese patient and physician needs, long-term commercial and regulatory experience, and strong presence as a leading company in Japan.

Novo Acquires Xellia for US$ 700 Million

May 22, 2013

Novo A/S, the holding company of Denmark's Novo Nordisk, has acquired Xellia Pharmaceuticals and purchased all shares of the group for approximately US$ 700 million.

Pfizer Halts Phase III Trial of Cancer Drug in NHL Due to Futility

May 22, 2013

Pfizer has discontinued a Phase III study of its investigational cancer drug, inotuzumab ozogamicin, in relapsed or refractory aggressive non-Hodgkin lymphoma (NHL) after it failed to show benefit in overall survival.

AbbVie and Galapagos Extend GLPG0634 Collaboration

May 21, 2013

AbbVie and Galapagos have extended their collaboration on the clinical development of GLPG0634 to include Crohn's disease.

AstraZeneca Provides Update on Oncology Pipeline

May 20, 2013

AstraZeneca announced that three of its cancer compounds—moxetumomab pasudotox, olaparib and selumetinib—will be moving forward to Phase III clinical development. Oncology is one of the company's core therapy areas and accelerating the development of a number of new molecular entities in its pipeline is a strategic priority.

Amgen Forms New Joint Venture to Commercialize Vectibix in China

May 13, 2013

Amgen and Zhejiang Beta Pharma have signed an agreement to form a joint venture to commercialize Amgen's Vectibix (panitumumab) in the Chinese market. The aim is to quickly and efficiently deliver Vectibix to patients in China. Vectibix is a fully human anti-epidermal growth factor receptor (EGFR) antibody approved by FDA for the treatment of metastatic colorectal cancer.

Lilly's Enzastaurin Disappoints in Phase III Trial

May 13, 2013

Eli Lilly reported that enzastaurin did not meet the primary endpoint in a Phase III study, which evaluated the agent as a monotherapy for the prevention of relapse in patients with diffuse large B-cell lymphoma (DLBCL).

Takeda to Acquire Inviragen for up to $250 Million

May 10, 2013

Takeda and US vaccines maker Inviragen jointly announced that they have entered into a definitive agreement for Takeda to acquire Inviragen for an upfront payment of US$35 million and future payments of up to US$215 million upon achievement of key commercial milestones, linked to the progress of clinical development.

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