Articles by Cynthia Challener, PhD - Pharmaceutical Technology

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Articles by Cynthia Challener, PhD

Sigma-Aldrich, The Scripps Research Institute Translating Research into Commercial Applications

New partnership aims to eliminate months from the typical transition time required to move chemistry from the laboratory into commercial applications.
Sep 11, 2013

New partnership aims to eliminate months from the typical transition time required to move chemistry from the laboratory into commercial applications.

Avoiding Glass Delamination with Early Product/Container Testing

Determining the potential for glass delamination before a product goes to market is the best way to ensure product safety and prevent expensive recalls.
Sep 11, 2013

Determining the potential for glass delamination before a product goes to market is the best way to ensure product safety and prevent expensive recalls.

Boehringer Ingelheim Pharmaceuticals Uses Two-Dimensional Ultrahigh-Pressure Liquid Chromatography in Process Development

2D-UHPLC enabled the simultaneous analysis of reaction conversion and enantiomeric excess in asymmetric hydrogenations
Sep 11, 2013

2D-UHPLC enabled the simultaneous analysis of reaction conversion and enantiomeric excess in asymmetric hydrogenations

Mechanical Control with Foam Granulation Well-Suited for Pharmaceutical Manufacturing

Foam granulation is much easier to control under mechanical dispersion conditions, which is where most industrial processes operate.
Sep 11, 2013

Foam granulation is much easier to control under mechanical dispersion conditions, which is where most industrial processes operate.

Novartis Making Moves to Increase Biologics Manufacturing Capability

Novartis half-billion dollar investment in a new biologics production plant in Singapore represents a strategic commitment to its growing biologics portfolio.
Sep 11, 2013

Novartis? half-billion dollar investment in a new biologics production plant in Singapore represents a strategic commitment to its growing biologics portfolio.

Examining the Role of Cocrystals in Drug Development and Manufacturing

A recent FDA guidance places greater attention on cocrystals as a tool in solid-dosage formulation.
Sep 1, 2013

A recent FDA guidance places greater attention on cocrystals as a tool in solid-dosage formulation.

Advancing API Synthesis

Commercial-scale amide formation and an improved process route for a tetracycline derivative are some recent developments in API synthesis.
Sep 1, 2013

Commercial-scale amide formation and an improved process route for a tetracycline derivative are some recent developments in API synthesis.

UCLA Researchers Develop Nanocapsule for Targeted Delivery of Large-Molecule APIs

Reversible nanoencapsulation technology may make it possible to deliver high molecular weight drugs directly to target cancer cells, increasing efficacy and reducing side effects.
Aug 28, 2013

Reversible nanoencapsulation technology may make it possible to deliver high molecular weight drugs directly to target cancer cells, increasing efficacy and reducing side effects.

Catalent Moves Forward with New Single-Use Biopharmaceutical Manufacturing Facility

Extensive adoption of single-use technologies and unidirectional flow reduces cross-contamination risk in the companys new biomanufacturing facility.
Aug 28, 2013

Extensive adoption of single-use technologies and unidirectional flow reduces cross-contamination risk in the company?s new biomanufacturing facility.

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Jim Miller Outsourcing Outlook Jim MillerCMO Industry Thins Out
Cynthia Challener, PhD Ingredients Insider Cynthia ChallenerFluorination Remains Key Challenge in API Synthesis
Marilyn E. Morris Guest EditorialMarilyn E. MorrisBolstering Graduate Education and Research Programs
Jill Wechsler Regulatory Watch Jill Wechsler Biopharma Manufacturers Respond to Ebola Crisis
Sean Milmo European Regulatory WatchSean MilmoHarmonizing Marketing Approval of Generic Drugs in Europe
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