Articles by Bruno C. Hancock - Pharmaceutical Technology

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Articles by Bruno C. Hancock

Bruno C. Hancock

scientist

Bruno C. Hancock is a scientist in the solids development group at Pfizer.

Articles
The Effect of Mill Type on Two Dry-Granulated Placebo Formulations
November 2, 2008

The authors evaluate the effect of various mill types on particle-size distribution, flowability, tabletability, and compactibility.

Development of an Improved Fluidization Segregation Tester for Use with Pharmaceutical Powders
December 2, 2006

This article describes the design and development of a material-sparing fluidization segregation tester for use with pharmaceutical powders. This tester offers several improvements over the current ASTM standardized test practice. Less than 20 mL of material is required to characterize the fluidization segregation potential of a sample. Features of the tester include powder containment for potent compounds, in-process monitoring of the fluidization conditions, and sample retrieval without the need for subsampling or riffling for typical analyses.

X-ray Microtomography of Solid Dosage Forms
April 2, 2005

X-ray microtomography has great potential for improving the understanding of the structural features of solid dosage forms and the changes in those features during manufacturing, handling, and storage.This article describes the basic principles of the technique and provides examples of its potential applications.

X-ray Microtomography of Solid Dosage Forms
April 1, 2005

X-ray microtomography has great potential for improving the understanding of the structural features of solid dosage forms and the changes in those features during manufacturing, handling, and storage. This article describes the basic principles of the technique and provides examples of its potential applications.

The Relative Densisties of Pharmaceutical Powders, Blends, Dry Granulations, and Immediate-Release Tablets
April 2, 2003

The authors provide a combined source of density data and show that denity can be used as an equipment-independent sclaing parameter in the manufacture of common pharmaceutical solids.

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