Articles by Charlie Martin - Pharmaceutical Technology

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Articles by Charlie Martin

Charlie Martin

Charlie Martin is a general manager at Leistritz North America, tel. 908.685.2333, ext 616.

Devolatilization/Solvent Extraction via Twin Screw Extrusion
April 23, 2014

Devolatilization (DV) is the process by which various amounts of unreacted monomer, solvent, water, or other undesirable volatile contaminants are removed from a polymer melt. A twin-screw extruder (TSE) is a device that is commonly utilized to compound polymer formulations to facilitate specific end-product performance. Oftentimes, there are chase impurities in the polymeric system that needs to be cleansed, sometimes as a result of tighter governmental or commercial standards, or due to the deleterious effects the residuals may have on final product properties.

Melt Extrusion: Shaping Drug Delivery in the 21st Century
November 1, 2010

The authors provde a review of melt extrusion's evolution and applications in the pharmaceutical industry. This article is part of a special Drug Delivery issue.

Continuous Mixing of Solid Dosage Forms via Hot-Melt Extrusion
October 2, 2008

The author describes the benefits, processes, and practicality of using hot-melt extrusion to mix active pharmaceutical ingredients with pharmaceutical-grade polymers.


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