Articles by Paul Lopolito - Pharmaceutical Technology

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Articles by Paul Lopolito

Paul Lopolito


Paul Lopolito is a technical services specialist at STERIS, Mentor, OH.

Articles
Rouge & Biofilm: Compounding Cleaning Challenges
July 30, 2014

Rouge and biofilm are commonly found in pharmaceutical manufacturing vessels and process piping. The presence of rouge on stainless steel surfaces may promote the development of biofilm and make it more difficult to remove. A robust cleaning and derouging procedure followed by process disinfection can be effective in controlling microbial contamination associated with biofilm.

Addressing Rouge in Biopharmaceutical Manufacturing Systems
September 15, 2010

The author describes the types and sources of rouge and explains ways to prevent and mitigate this problem.

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Jim Miller Outsourcing Outlook Jim MillerCMO Industry Thins Out
Cynthia Challener, PhD Ingredients Insider Cynthia ChallenerFluorination Remains Key Challenge in API Synthesis
Marilyn E. Morris Guest EditorialMarilyn E. MorrisBolstering Graduate Education and Research Programs
Jill Wechsler Regulatory Watch Jill Wechsler Biopharma Manufacturers Respond to Ebola Crisis
Sean Milmo European Regulatory WatchSean MilmoHarmonizing Marketing Approval of Generic Drugs in Europe
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