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Nanotechnology Advances in Drug Delivery
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| By
Patricia Van Arnum
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Nanotechnology is emerging as a tool for resolving challenges in delivering poorly water soluble and highly potent drugs.
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Solubility, Polymorphism, Crystallinity, Crystal Habit, and Drying Scheme of (R, S)-(±)-Sodium Ibuprofen Dihydrate
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| By
Tu Lee
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Ying Hsiu Chen
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Chyong Wen Zhang
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The racemic compound (R, S)-(±)-ibuprofen is a popular and well understood active pharmaceutical ingredient, but it has several disadvantageous formulation properties such as poor solubility, low melting point, and potential esterification with excipients containing an hydroxyl group. The authors investigate the use of an (R, S)-(±)-ibuprofen salt to evaluate these problems using various analytical methods to determine the polymorphism, crystallinity, and drying scheme.
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Building Monoclonal Antibody Production
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| By
Patricia Van Arnum
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Pharma companies and CMOs build positions in mAbs.
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Pharmaceutical Technology's Manufacturers' Rankings
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| By
Erik Greb
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Patricia Van Arnum
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Pharmaceutical Technology's Annual Manufacturers' Rankings provides perspectives on revenues, product positioning, R&D spending, pharmaceutical manufacturing activity, and capital projects of the major drug companies.
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Balancing Act
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| By
Michelle Hoffman
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Perhaps Congress can help FDA meet its multiple oversight demands.
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Membrane cassettes support high mass transfer
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Pall Corp. recently unveiled its "Omega T" series membrane cassettes for biopharmaceutical processing applications involving high protein concentrations.
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Air dryers save energy
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The "SRC" series cycling dryers offered by Sullair, unlike similar dryers, sense the presence of a partial load.
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In the Spotlight
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Editors' Picks of Pharmaceutical Science & Technology Innovations
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In The Field
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Boston, MA (May 8)—The global biotechnology industry showed several positive signs in 2006, including increases in overall revenues and financing, although the industry as a whole continues to operate at a loss, according to Ernst & Young's (New York, NY, www.ey.com) annual analysis of the biotechnology industry. Its report, "Beyond Borders 2007," was issued at the Biotechnology Industry Organization's (BIO, www.bio.org) annual conference and exhibition, which was held in Boston May 6–9.
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