|
|
|
|
|
Less Is More for Low-Dose Drugs
|
|
|
| By
Heinz Sucker, PhD
|
|
|
|
Developers of low-dose drugs in solid oral dosage forms will find theoretical considerations and practical advice in a new book.
|
|
|
|
Novel Approaches for Oral Insulin Delivery
|
|
|
| By
S. Dhawan
,
S. Chopra
,
R. Kapil
,
D. Kapoor
|
|
|
|
The authors review various oral drug delivery systems that have been explored to increase patient compliance for insulin.
|
|
|
|
A Tale of Two Techniques
|
|
|
| By
Erik Greb
|
|
|
|
Pan coating has been the preferred method of coating tablets for more than 20 years, but core coating is becoming more popular.
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Modification and Characterization of Gellan Gum
|
|
|
| By
Dhiren P. Shah
,
Girish K. Jani
|
|
|
|
The authors modified gellan gum using microwave technology and showed it can be used as an excipient in tablet formulations.
|
|
|
|
Cleaning Verification: Method Development and Validation
|
|
|
| By
Elizabeth Galella
,
Scott Jennings
,
Madhavi Srikoti
,
Elizabeth Bonasso
|
|
|
|
The authors discuss the theory of ion mobility spectrometry, its benefit over HPLC analysis in cleaning verification, and the experimental considerations for method validation and validation.
|
|
|
|
|
|
|
|
|
The Biopharmaceutical Manufacturing Survey
|
|
|
| By
Michelle Hoffman
|
|
|
|
A Pharmaceutical Technology report looks at trends in biopharmaceutical manufacturing. This article contains bonus online-exclusive material.
|
|
|
|
Next-Generation Facilities for Monoclonal Antibody Production
|
|
|
| By
Niels Guldager
|
|
|
|
Dramatic increases in yields from cell lines and the increasing popularity of single-use technologies will change the way we look at future bioprocessing facilities and process designs.
|
|
|
|
Large-Scale Manufacture of Therapeutic Human Stem Cells
|
|
|
| By
Robert J. Thomas
,
David J. Williams
|
|
|
|
Large-scale manufacturing of human stem cells for therapeutic use is a leap in technology and science for the current biotechnology industry.
|
|
|
|
Stabilization of Interferon alpha-2b in a Topical Cream
|
|
|
| By
Praveen Kumar
,
Ravinderjit Batta
,
Geriene LaBine
,
Jinghui Shen
,
Kim Gaspar
,
John Docherty
,
Marianna Foldvari
|
|
|
|
The authors describe a proprietary process for producing a stable, topical interferon alpha-2b formulation that can deliver large drug molecules into the skin or mucosa.
|
|
|
|
Debunking the Bottleneck Myth
|
|
|
| By
Günter Jagschies
|
|
|
|
A look at the true cost-drivers of cell-culture production.
|
|
|
|
Using NIR to Move Bioprocessing into a PAT Framework
|
|
|
| By
Todd Strother
|
|
|
|
The author provides a review of PAT and tools such as near infrared analysis that may facilitate the use of PAT in the biopharmaceutical sector.
|
|
|
|
Integration of PAT in Biopharmaceutical Research: A Case Study
|
|
|
| By
Kjell François
,
Mathieu Streefland
,
Rebecca Vangenechten
,
Leo Hammendorp
|
|
|
|
This case study describes the implementation of process analytical technology on the cultivation process step of a whole-cell vaccine against whooping cough disease.
|
|
|
|
Outsourced Vaccine Development
|
|
|
| By
Phil Ball
,
Maria Lusk
|
|
|
|
The authors discuss how strategic outsourcing to contract manufacturing organizations that have technical and regulatory expertise can add further value during vaccine development.
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Wasting Away
|
|
|
| By
Control, a senior compliance officer
|
|
|
|
Some GMP agents seem to find a way to squander time, money, and common sense.
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Can Industry Learn to Share?
|
|
|
| By
Angie Drakulich
|
|
|
|
The regulators are doing it. But industry's fear of sharing information may leave them behind.
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Report From: India
|
|
|
| By
A. Nair
|
|
|
|
Patent infringement claims and a lack of clear global trade distribution routes may be unraveling the country's generic-drug export industry.
|
|
|
|
|
|
|
|
|
In the Spotlight
|
|
|
|
Editors' Picks of Pharmaceutical Science & Technology Innovations
|
|
|
|
|
|
|
|
|
|
