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Trends in Bioprocessing
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Michelle Hoffman
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The second annual Pharmaceutical Technology Bioprocessing Survey offers a snapshot of the industry following 2009's megamergers.
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Industrialized Production of Human iPSC-Derived Cardiomyocytes for Use in Drug Discovery and Toxicity Testing
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| By
Blake Anson
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Emile Nuwaysir
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Brad Swanson
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Wen Bo Wang
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The authors describe an industrialized process for the manufacture of iPSC-derived human cardiomyocytes. This article is part of a special issue on Bioprocessing and Sterile Manufacturing.
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A Detail View of Single-Use Equipment Opportunities
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Thomas Paust
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Detelv Szarafinksi
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Christian Manzke
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Thorsten Peuker
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Maik W. Jornitz
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The authors propose increased use of single-use technologies in biopharmaceutical manufacturing to achieve operational excellence without compromising product quality.
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Disposable Technologies for Fill-Finish of Clinical-Trial Materials
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Tony Pidgeon
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The author examines the use and advantages of disposable technologies in the fill–finish of sterile pharmaceutical products and how these technologies can reduce costs and time in producing clinical-trial materials.
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Cost Advantages of Single-Use Technologies
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Niels Guldager
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Single-use technologies can help simplify equipment and facility design, thus bringing cost advantages. But how are these cost advantages realized and what criteria can be used to assess their impact? This article is part of a special issue on Bioprocessing and Sterile Manufacturing.
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Integrated Microfluidic LC-MS
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Maggie Bynum
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Tomasz Baginski
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Kevin Killeen
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Rodney Keck
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The authors describe a new microfluidic-based workflow that integrates and automates glycan cleaveage, purification, and chromatographic separation onto a microfluidic liquid chromatography–mass spectrometry chip for MS detection.
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Gamma Irradiation in the Pharmaceutical Manufacturing Environment
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Betty Howard
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The author reviews the benefits, challenges, and considerations to be made when selecting a gamma-irradiation sterilization method.
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The Myth Called "Sterility"
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James P. Agalloco
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James E. Akers
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The authors propose a process-centric approach for carrying out aseptic-processing and suggest further dialogue. This articles contains bonus online-exclusive material.
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An Overview of Rapid Microbial-Detection Methods
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Erik Greb
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Pharmaceutical Technology talked to drugmakers, equipment vendors, and service providers to learn more about the advantages and disadvantages of rapid microbial-detection methods.
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Surface Plasmon Resonance as an Analytical Tool for Bioprocessing
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| By
Michelle Hoffman
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A Q&A with GE Healthcare
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