Pharmaceutical Technology, Jul 2, 2010 - Pharmaceutical Technology

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Pharmaceutical Technology, Jul 2, 2010
Online Exclusives
A Cost- and Environmentally Effective Approach to Supplying Nitrogen Gas to Pharmaceutical Manufacturing Industrial Facilities
By Mario Bolivar , Peter Froehlich
The authors argue that the cost of generating nitrogen via an in-house gas generator is considerably lower than the cost of using fractional distillation to generate liquid nitrogen.
Special Report
The Hour of the Particle
By Erik Greb
Is now the time for multiparticulates to shine as a controlled-release solution?
Exploring the Tools in Nanoparticle Analysis
By Patricia Van Arnum
Nanotechnology is an important area of drug and biomedical research, and advancing nano-analysis is crucial for its further development.
Comparison of Superdisintegrants in Orally Disintegrating Tablets
By Yeli Zhang , Amy Wrzesinski , Marley Moses , Holly Bertrand
The functionality and performance of three types of commercial superdisintegrants were evaluated in the application of orally disintegrating tablets.
Statistical Considerations in Design Space Development (Part I of III)
By Stan Altan , James Bergum , Lori Pfahler , Edith Senderak , Shanthi Sethuraman , Kim Erland Vukovinsky
The authors discuss the statistical tools used in experimental planning and strategy and how to evaluate the resulting design space and its graphical representation.
Novel Suppository Design for HIV Chemoprophylaxis
By Timothy J. Smith , Lara Haddad , Soraia Faizyar , Evelyn Valdez , Elizabeth Gramer , Layla S. Derreja , Stefany M. Bowers
Technical Note: The authors investigated the variables important for calcium-alginate formation as well as dissolution.
Ingredients Insider
Augmenting Excipient Functionality
By Patricia Van Arnum
Excipient manufacturers expand their products, services, manufacturing capacity, and technology positions.
From The Editor
A Word to the Unwise
By Michelle Hoffman
After a spate of industrial disasters, the public seeks greater oversight of corporations—so does FDA.
PharmTech Talk
A Glass Act
By Erik Greb
Duke University researchers have found a possible alternative to lyophilization.
Agent-in Place
The Cold Shoulder
By Control, a senior compliance officer
Reports of overlooked controls, dropped pallets, and misplaced documents leave a chill in the air.
Report from India
By A. Nair
As generic divisions become the most-wanted acquisitions of Big Pharma, India's domestic industry may be thinning out.
In the Spotlight
In the Spotlight
Editors' picks of pharmaceutical science and technology innovations.
Washington Report
Transparency to Alter FDA and Industry Practices
By Jill Wechsler
More information may be released to improve public understanding of regulatory policies.
Statistical Solutions
Statistical Solutions: On the Verge of Significance: Why 5%
By Lynn D. Torbeck
A history of the selection of the widely used significance level leaves much to be desired.
Outsourcing Outlook
Be Careful for What You Wish
By Jim Miller
Rising labor costs in China may result in increased competition for higher value services.
Industry Leaders: Q&A
Q&A with Metrics' David Varley
Varley, director of commercial operations, discusses one-stop shops and timelines.
Top-to-Bottom Collaboration
By Ken Johnson
To continue innovating, the biopharmaceutical sector needs support from all levels.


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Finance development of drugs to treat/prevent disease.
Oversee medical treatment of patients in the US.
Provide treatment for patients globally.
All of the above.
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Finance development of drugs to treat/prevent disease.
Oversee medical treatment of patients in the US.
Provide treatment for patients globally.
All of the above.
No government involvement in patient treatment or drug development.
Jim Miller Outsourcing Outlook Jim MillerOutside Looking In
Cynthia Challener, PhD Ingredients Insider Cynthia ChallenerAdvances in Large-Scale Heterocyclic Synthesis
Jill Wechsler Regulatory Watch Jill Wechsler New Era for Generic Drugs
Sean Milmo European Regulatory WatchSean MilmoTackling Drug Shortages
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