Equipment and Processing Report, Feb 15, 2012 - Pharmaceutical Technology

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Equipment and Processing Report, Feb 15, 2012
Production Lines
Mid-Size Extruders Enable Scale-Up of Hot-Melt Extrusion
By Jennifer Markarian
With the increasing use of hot-melt extrusion, extruder manufacturers have developed mid-size twin-screw extruders that facilitate process development and scale-up to commercial processes.
In the Mixer
Comparing Lyophilization in Vials and Dual-Chamber Systems
By Joerg Zimmermann
The author discusses the relative advantages and disadvantages of lyophilization in vials and dual-chamber systems.
Troubleshooting
Determining Whether Dry-Dispersion Can Be Used in a Laser-Diffraction System
We need to measure the particle size of a moisture-sensitive powder. We would like to use dry analysis on our laser-diffraction system, but the particles are fragile and we're struggling to get robust results. Is wet measurement with a nonaqueous solvent the only option?
Editor's Picks
February 2012 Editor's Picks: Products from ACS Valves and G-Con Manufacturing
PharmTech's monthly newsletter, Equipment and Processing Report, reviews the Editor's Picks for the February 2012 edition from ACS Valves and G-Con.

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