Equipment and Processing Report, Feb 15, 2012 - Pharmaceutical Technology

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Equipment and Processing Report, Feb 15, 2012
Production Lines
Mid-Size Extruders Enable Scale-Up of Hot-Melt Extrusion
By Jennifer Markarian
With the increasing use of hot-melt extrusion, extruder manufacturers have developed mid-size twin-screw extruders that facilitate process development and scale-up to commercial processes.
In the Mixer
Comparing Lyophilization in Vials and Dual-Chamber Systems
By Joerg Zimmermann
The author discusses the relative advantages and disadvantages of lyophilization in vials and dual-chamber systems.
Troubleshooting
Determining Whether Dry-Dispersion Can Be Used in a Laser-Diffraction System
We need to measure the particle size of a moisture-sensitive powder. We would like to use dry analysis on our laser-diffraction system, but the particles are fragile and we're struggling to get robust results. Is wet measurement with a nonaqueous solvent the only option?
Editor's Picks
February 2012 Editor's Picks: Products from ACS Valves and G-Con Manufacturing
PharmTech's monthly newsletter, Equipment and Processing Report, reviews the Editor's Picks for the February 2012 edition from ACS Valves and G-Con.

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Survey
FDASIA was signed into law two years ago. Where has the most progress been made in implementation?
Reducing drug shortages
Breakthrough designations
Protecting the supply chain
Expedited reviews of drug submissions
More stakeholder involvement
Reducing drug shortages
70%
Breakthrough designations
4%
Protecting the supply chain
17%
Expedited reviews of drug submissions
2%
More stakeholder involvement
7%
View Results
Eric Langerr Outsourcing Outlook Eric LangerRelationship-building at Top of Mind for Clients
Cynthia Challener, PhD Ingredients Insider Cynthia ChallenerRisk Reduction Top Driver for Biopharmaceutical Raw Material Development
Jill Wechsler Regulatory Watch Jill Wechsler Changes and Challenges for Generic Drugs
Faiz Kermaini Industry Insider Faiz KermainiNo Signs of a Slowdown in Mergers
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