Pharmaceutical Technology Europe-03-07-2011

Pharmaceutical Technology Europe

Direct Compression Versus Granulation

March 07, 2011

Special Feature

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Compressed tablets are the most widely used solid dosage form so they must satisfy a number of physical requirements in terms of hardness, disintegration ability, friability and uniformity.

One-Pot Processing And The Benefits For Granulation

March 07, 2011

Special Feature

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One-pot processing is a term that includes any technology that combines different unit operations of a pharmaceutical production process into one machine.

News

March 07, 2011

News

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With the future of healthcare revolving more and more around patient empowerment, data and healthy outcomes, the big question is can the traditionally slow and reserved pharma industry keep up with the new era?

Moisture-Activated Dry Granulation

March 07, 2011

Special Feature

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Moisture Activated Dry Granulation (MADG) was developed in response to the difficulties experienced with wet granulation, in terms of endpoint, drying and milling. Wet granulation process endpoint is very sensitive to granulation time and shear. The wet granules need to be dried to a narrow range of moisture contents, which is difficult. The dried granules need to be milled, but the milled granules often have either too many fines or too many coarse particles (or both) - an undesirable bimodal distribution.

Drug Scandal Shocks France

March 07, 2011

Industry Insider

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In France, public confidence in health authorities and pharmaceutical industry has been shaken by a safety scandal over the drug Mediator (benfluorex hydrochloride).

Improving Solid Dosage Forms With Dry Granulation

March 07, 2011

Peer-Reviewed Research

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Although tablet manufacture is traditionally a batchbased wet granulation process, there are many advantages to be gained by adopting dry granulation, including lower costs and increased yields.

The Benefits Of Tablet Tooling Standardisation

March 07, 2011

Manufacturing

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Tooling standardisation in the tablet manufacturing industry is a topic that has concerned tabletting professionals for decades.

Pros And Cons Of Roll Compaction

March 01, 2011

Special Feature

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There are two types of widely used dry granulation methods: slugging and roll compaction. Currently, roll compaction is preferred to slugging because it offers greater capacity and ease of process control.