Pharmaceutical Technology-05-02-2006

Pharmaceutical Technology

In the Loop: Continuous Chromatography for Chiral (and Other) Separations

May 02, 2006

Articles

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5

With single-enantiomer separations dominating the blockbuster charts, simulated moving bed chromatography and other multicolumn continuous chromatographic processes offer a quick route to clinical trial materials, along with the resolution, economy, and scalability to support tons-per-year production.

An Approach Using Bezier Curves to Control pH and Decrease Enzyme Inactivity

May 02, 2006

Articles

30

5

Using Bezier curves, an experimental process controller has been developed for biosynthesis applications in which the inactivity of a pH-sensitive enzyme must be decreased. By taking into account various control scenarios of pH and growth rate, as well as the physical and chemical characteristics of the environment, a suitable human-machine interface can be developed.

Making it Personal

May 02, 2006

This Time Around

30

5

At this year's BIO conference, US Health and Human Services Secretary Mike Leavitt predicted that over the coming decade, "Medicine will be transformed from an instinctive art of alleviating symptoms to a science of personalized healthcare." Is industry ready?

May 2006

May 02, 2006

In the Field

30

5

Gottlieb challenges industry. First GenerationNext Awards. Implementing PAT. Optimizing site risk. RFID in the supply chain. Biodegradable polyketals. Global drug-market growth moderates.