Pharmaceutical Technology Europe
- Pharmaceutical Technology Europe-06-01-2011
- Volume 23
- Issue 6
A Comparison of Three Extrusion Systems (Part II)
The authors compare three systems of single-screw extrusion using binary formulations for their suitability for producing pellets of various formulations and under various spheronization conditions.
By Amelie Desire, Bruno Paillard, Joel Bougaret, Michel Baron and Guy Couarraze
The authors compare three systems of single-screw extrusion (i.e., radial, dome, and axial) using binary formulations (i.e., microcrystalline cellulose, and active material) for their suitability for producing pellets of various formulations and under various spheronization conditions. Pellets were characterized by their size and shape, and by their structural and mechanical properties. The experimental design showed high variation between the three extrusion systems.
This article was also published in our US sister publication Pharmaceutical Technology and can be read
Articles in this issue
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Optimising High-Potency Manufactureover 14 years ago
The EMA And EU Expansionover 14 years ago
The Rising Uptake Of Immediate Release And ODT Formulationsover 14 years ago
Table Testing Techniquesover 14 years ago
Celebration And Cinemaover 14 years ago
Newsover 14 years ago
The Influence Of Superdisintegrants On Immediate Releaseover 14 years ago
The Single-Use Technology World Tourover 14 years ago
Annex 11: Progress in EU Computer Systems Guidelinesover 14 years ago
New Annex 11: Enabling InnovationNewsletter
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