Formulation

Jan 01, 2003
Pharmaceutical Technology Europe
Medicines and excipients are inseparable, with few exceptions - one cannot exist without the other. The Pharmaceutical Quality Group and other international bodies have developed good manufacturing practice (GMP) standards and guidelines to facilitate the effective supply of excipients. This article discusses the definition and significance of excipients, and highlights the importance of implementing the correct excipient manufacturing controls and standards.
Dec 01, 2002
Pharmaceutical Technology Europe
Spectroscopy using light is a familiar technique and the electromagnetic spectrum from UV to IR is routinely employed. This article looks at the advantages and applications of spectroscopy using sound waves, with special reference to pharmaceutical research.
Nov 01, 2002
Pharmaceutical Technology Europe
The aim of this work was to investigate the compactibility, compressibility and drug release behaviour of different fractions of a commercially available ethyl cellulose.
Oct 01, 2002
Pharmaceutical Technology Europe
Using melt extrusion to prepare glass solutions of poorly water-soluble drugs with hydrophilic excipients offers an exciting and advantageous alternative to existing formulation methods such as spray-drying and co-melting. Investigating potential methods to increase water solubility begins early in drug development. Techniques described in this paper show how only a small quantity of drug can be used to determine its suitability for melt extrusion, allowing the method to be considered at the same time as salt screening and particle size reduction work, and could speed up the formulation process.
Jul 01, 2002
Pharmaceutical Technology
Extensive research has been conducted to improve the solubility and permeability of acetazolamide in hopes that a topical formulation for the treatment of glaucoma can be developed.
May 01, 2002
Pharmaceutical Technology
By Pharmaceutical Technology Editors
A knowledgeable and experienced contract service provider can help in the development and success of an inhalation drug product.
Sep 01, 2001
Pharmaceutical Technology
Both academia and industry have been encouraged to generate quick­dissolving dosage forms as the demand for fast­disintegrating tablets and capsules has steadily increased.
Sep 01, 2001
Pharmaceutical Technology
This study attempts to determine the combination of excipients found in commercial ASA products that would be suitable for use in an aqueous enteric film­coating process.
Sep 01, 2001
Pharmaceutical Technology
This comparative study suggests that pregelatinized starches are superior to natural starches in terms of improving the plastic deformation in tablet formulations during compression.
Sep 01, 2001
Pharmaceutical Technology
The author assesses the compressibility of Plasdone S- 630 copovidone-based tablet formulations using roller-compaction and direct-compression processes.
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