How to minimize the limitations of roll compaction

The application of roll compaction as a dry granulation method for three different drug types — herbal dry extract, poorly compactable drug and a sustained-release matrix tablet — was examined. Despite some disadvantages, such as the loss of reworkability of roll compacted substances, the authors confirmed the feasibility and benefits of roll compaction for each case.
Dec 01, 2009
Volume 21, Issue 12