Process Development

May 15, 2018
Pharmaceutical Technology
Advanced data analytics tools are used by industry to find the golden nuggets in historical data, to aid in process development, to fine-tune production, and to achieve long-term improvements in product quality and throughput.
May 15, 2018
Pharmaceutical Technology
Aerobic bioprocesses are highly dependent upon the oxygen transfer rate (OTR) from sparged to dissolved gas. The relatively low solubility of oxygen, however, makes the choice of mixer impeller configuration a critical design factor for the bioreactor vessel. This article describes a series of experiments and computational fluid dynamics (CFD) simulations to detail the effect of mixer configuration on the efficiency and effectiveness of a bioreactor vessel with respect to blend time and mass transfer.
May 07, 2018
Smaller review divisions will bring experts closer to decision processes and reduce bottlenecks, FDA leaders say.
May 02, 2018
Pharmaceutical Technology
Determining the right process conditions for a freeze-drying cycle requires an understanding of the effect of each step on the drug product.
Apr 17, 2018
By Pharmaceutical Technology Editors
Industry experts will discuss lyophilization best practices and continuous manufacturing for biopharmaceuticals.
Apr 02, 2018
Pharmaceutical Technology
Pharma 4.0 envisions highly efficient automated processes, which could be continuous, batch, or a hybrid of these, driven by an integrated manufacturing control strategy.
Mar 09, 2018
By Pharmaceutical Technology Editors
The Natoli AIM Data Acquisition and Analytical Software for Natoli’s NP-RD10A single-station tablet press speeds research and development.
Mar 08, 2018
By Pharmaceutical Technology Editors
GlobalData reports the need to shift away from egg-based manufacturing of vaccines in light of influenza-related deaths.
Mar 02, 2018
Pharmaceutical Technology
Assessing potential formulation and manufacturing issues in early development phases can improve a drug’s chances for success.
Feb 20, 2018
By Pharmaceutical Technology Editors
The study suggests that circumventing evolution in cell factories can enable the commercialization of new biobased chemicals to large-scale.
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