|Articles|August 1, 2011

Pharmaceutical Technology Europe

  • Pharmaceutical Technology Europe-08-01-2011
  • Volume 23
  • Issue 8

Understanding Fluidized-Bed Granulation

This study demonstrates the beneficial use of a spatial-filter velocimetry particle-size analyzer during granulation.

By A. Burggraeve, T. Van Den Kerkhof, M. Hellings, J.P. Remon, C. Vervaet and T. De Beer

The authors incorporated a particle-size analyser into a laboratory-scale top-spray fluid-bed granulator to monitor granule size distribution (GSD) continuously during granulation. A two-level full-factorial design was used to study the influence of several process and formulation variables on the end-product GSD, measured in-line with spatial-filter velocimetry (SFV).

This article was also published in our US sister publication Pharmaceutical Technology and can be read here.

Articles in this issue

about 15 years ago

Improving API Synthesis

about 15 years ago

Movin' On Out

about 15 years ago

The Many Varieties Of 'Emerging'

about 15 years ago

News

about 15 years ago

Managing Information Overload

about 15 years ago

The Importance Of Filter Testing

about 15 years ago

Making A Mark In Emerging Markets

about 15 years ago

Croatia, Pharma and Corruption

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