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Pharmaceutical Technology-06-02-2006
Pharmaceutical Technology
Consumed with Consumables
June 02, 2006
Outsourcing
30
6
The laboratory supplier landscape is undergoing a radical makeover.
The Fine Print
June 02, 2006
Agent-In-Place
30
6
I always suspected that our purchasing manager had agreed to this just to save money . . .
Thermal Effusivity and Power Consumption as PAT Tools for Monitoring Granulation End Point
June 02, 2006
Articles
30
6
Thermal effusivity and power consumption may help predict granulation end point in high-shear granulators. In this study, power consumption was monitored and compared with percent relative standard deviation (RSD) on thermal effusivity measured at-line. Lactose monohydrate, microcrystalline cellulose, and magnesium oxide were granulated, and the effect of load size on granule growth in a fixed-volume granulator was evaluated using three load levels. Load size, liquid addition rate, and impeller speed were measured, and the correlation among RSD on effusivity, power consumption, mean granule specific surface area, and granule compressibility index were determined.
Better Process Understanding Improves Quality, Lowers Risk
June 02, 2006
Viewpoint
30
6
Predictable outcomes lead to greater manufacturing efficiency and speed time to value.
Standing Up for the Little (Molecule) Guy
June 02, 2006
From The Editor
30
6
Does "personalized medicine" mean personalized treatment or personalized molecules, custom made for a patient's specific biology?
A Capacity Wave in Biologics Manufacturing
June 02, 2006
Articles
30
6
CMOs account for 20–30% of biopharm production. Big Pharma also is filling the biologics supply chain.
Interphex Focuses on Counterfeit Prevention
June 02, 2006
Packaging Forum
30
6
Interphex provided an opportunity to examine the latest pharmaceutical packaging concepts and packaging machines.
Outsourcing Solid Dosage Manufacturing
June 02, 2006
Articles
30
6
The biggest single recent trend in outsourcing solid-dosage processing has been the movement toward discovery and synthesis of more potent active pharmaceutical ingredients.
The Merits of Failure
June 02, 2006
This Time Around
30
6
If there's one word I (and probably most people) have come to fear more than all others, it's "failure." We've been conditioned since grade school that failure is shameful and punishment worthy. Maybe even something we should tuck away in our knapsack, sneak past Mom and Dad, tear into little pieces, and hide under the carpet.
FDA Moves to Transform Plant Inspection System
June 02, 2006
Washington Report
30
6
ORA leadership looks to staff redeployment and risk management to ensure product quality despite diminishing resources.