|Articles|March 7, 2022

Fluidized-Bed granulation Top-Spray versus Tangential-Spray Support for Decision-Making

Author(s)Diosna

Fluidized-bed granulation nowadays is an integral part of the production of solid dosage forms. In the pharmaceutical industry, fluidized-bed granulation using top-spray technology is a very widely used method. However, the tangential-spray technique is establishing itself as an alternative thanks to the numerous advantages it offers.


Related to this article

Glass vial, pipette and woman scientist in laboratory for medical study, research or experiment. Test tube, dropper and professional female person with chemical liquid for pharmaceutical innovation. | Image Credit: ©HockleyMedia24/peopleimages.com -stock.adobe.com
Equivalence test using two one-sided tests are widely used for demonstrating the comparability of treatment effects in different research fields. The method described in the manuscript aims to use simulations in Microsoft Excel to compute power for 2 one-sided tests for two groups with unequal variances.
Complying with International Pharmacopoeias
Susan J. Schniepp, distinguished fellow with Nelson Labs, and Siegfried Schmitt, PhD, vice president, Technical, with Parexel, clear up some of the confusion about what does and does not need to be complied with regarding standards set by international pharmacopoeias.