Using Empty AAV Capsids to Reduce Inhibitory Effect of Neutralizing Antibodies on AAV Transduction

Jiu Jiang, Ph.D., Director at Absorption Systems, discusses a study conducted to investigate the potential utility of empty capsids of adeno-associated virus serotype AAV2 in overcoming the negative effect of neutralizing antibodies on AAV2-mediated transduction in an in vitro cell-based assay.