Pharmaceutical Technology-04-02-2006

Pharmaceutical Technology

New biocatalytic and chemocatalytic routes to chiral intermediates and developments in simulated-moving-bed and supercritical-fluid chromatography for resolving racemic mixtures.

Pharmaceutical Technology
Washington Report

April 02, 2006

The need to curb drug counterfeiting is spurring development of track-and-trace and product authentication technologies.

Pharmaceutical Technology
From The Editor

April 02, 2006

Hubert J.P. Schoemaker and William T. McCormick. Perhaps we could have not a special day, but just a moment to remember what we owe and who we we owe it to.

Pharmaceutical Technology
Outsourcing

April 02, 2006

Recent deals suggest companies are willing to pay up to get into CMC services.

In the Field
Pharmaceutical Technology

April 02, 2006

Eisai plans $105-million plant. Novartis to build plant in China. BMS building $660-million biologics facility. Slow adoption of RFID. Vaccines update. $14.7 billion in pharma construction in 2006. Chiron sells Betaseron to Schering. Baxter to develop cell based H5N1 vaccine. Drug sales up 5.4%, but growth slowing.

Performing D-value and population verification is critical in the acceptance criteria for allowing a new lot of biological indicators into a facility before acceptance and use of the lot in validation work or routine monitoring of sterilization cycles.

Pharmaceutical Technology
This Time Around

April 02, 2006

Despite worries that industry is slow to adopt anticounterfeiting technologies, the 2006 Interphex program is rife with new methods for securing the supply chain.

Absorption promoters and enhancers and enzyme inhibitors, either alone or in combination, can play an important role in improving the bioavailability of oral insulin.

Guidance for reducing the risk of dissolved ozone measurement and addresses proper installation, calibration, and verification to ensure the best possible answers from dissolved ozone analysis.

Pharmaceutical Technology

Senior management must be the champions of change in companies that are struggling financially or organizationally.

Pharmaceutical Technology
Agent-In-Place

April 02, 2006

Vitamin D and a sunny window shed som light on product stability.

Pharmaceutical Technology

Cell-culture technology and financial incentives give influenza vaccine makers a much-needed shot in the arm, but many downstream processing issues remain unaddressed.