|Articles|December 2, 2016

Pharmaceutical Technology

  • Pharmaceutical Technology-12-02-2016
  • Volume 40
  • Issue 12

Automated Microscope for Multimodal Imaging

Zeiss’s Axio Observer inverted microscope platform includes new automation features, allowing researchers to perform multimodal imaging of living and fixed specimens.

Zeiss’s Axio Observer inverted microscope platform includes new automation features, allowing researchers to perform multimodal imaging of living and fixed specimens. Among these features is Autocorr, a technology that allows adaption of immersion objectives to varying sample carriers and imaging conditions. The correction of spherical aberrations results in improved image contrast, higher resolution, and more efficient fluorescence detection. 

The microscope includes a new autoimmersion option that builds up and maintains stable water immersion without evaporation or air bubbles, and is compatible with multiple water immersion objectives in the nosepiece. The Axio Observer includes interfaces for imaging technologies, ranging from widefield transmitted light to 3D sectioning, fast and sensitive confocal super-resolution imaging, and structured illumination as well as photoactivated localization microscopy.


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