Ron Scarboro, Azurity Pharmaceuticals, explains how cross-functional development, disciplined reformulation, and post-approval metrics can help proven medicines work in everyday use.
|Articles|April 2, 2023
- Pharmaceutical Technology, April 2023
- Volume 47
- Issue 4
- Pages: 12
Automated mRNA Synthesis Kit
Author(s)Pharmaceutical Technology Editors
Bio-Rad Laboratories StarBright Blue and StarBright Yellow dyes are conjugated to flow validated antibodies, supporting flow cytometry panel design in immunology design.
Telesis Bio’s BioXp Select mRNA Synthesis Kit enables on-demand, automated synthesis of messenger RNA (mRNA). Beginning from the user’s plasmid DNA, the kit can deliver results overnight, enabling researchers to optimize discovery workflows more quickly.
Building on the company’s prior mRNA synthesis kit, which builds mRNA up to 1.8 kb in length starting from a DNA sequence as input, the new kit allows users to enter the sequence or linearized plasmid. This automates the entire workflow, allowing users to generate the final synthetic mRNA product in hours. The product also provides options for modified nucleosides.
Articles in this issue
over 3 years ago
Balancing Change and Certainty in Manufacturingover 3 years ago
Formulating Drugs for Continuous Processingover 3 years ago
Quality Challenges Associated with Cryo/Lyoprotectantsover 3 years ago
Packaging Becomes More Sustainableover 3 years ago
Accepting Alternative Approaches to Freeze Dryingover 3 years ago
Considerations for Analytical Testing for E&Lover 3 years ago
A New Hope for Children Living with HIVover 3 years ago
Kudos and Hurdles in Tackling Rare DiseasesRelated to this article
This week, drug formulation and manufacturing experts showcased their knowledge, and companies exhibited their products, at CPHI Milan.
FDA approves Teva’s Weltruza, a once-monthly subcutaneous olanzapine for schizophrenia whose copolymer depot eliminates post-injection monitoring.
Mitigating nitrosamine risk requires assessing each product individually, says Bram Baert, Global Head of Regulatory Affairs at Capsugel, and Sandrine Picco, Senior Analytical Specialist on Capsugel's Innovaform Accelerator Team, in this interview with PharmTech.
Jason Bertola, executive director of Commercial Development for the Advanced Synthesis Platform at Lonza in North America, explains the demand for spray drying and the hurdles involved with scale up, in an interview with PharmTech.
Ron Scarboro, Azurity Pharmaceuticals, explains when formulation robustness justifies added cost and which post-approval quality and supply metrics teams can track.
The winners of the CPHI Pharma Awards 2026 include a neurodegeneration platform, a track-and-trace packaging innovation, a enzymatic mRNA manufacturing technology, and a cell-free enzymatic biomanufacturing platform.
Richard Jaenisch explains why NAMs are compressing drug development faster than AI and what FDA's new nonclinical testing rule means for sponsors.
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