Pharmaceutical Technology Europe
- Pharmaceutical Technology Europe-06-01-2011
- Volume 23
- Issue 6
A Comparison of Three Extrusion Systems (Part II)
The authors compare three systems of single-screw extrusion using binary formulations for their suitability for producing pellets of various formulations and under various spheronization conditions.
By Amelie Desire, Bruno Paillard, Joel Bougaret, Michel Baron and Guy Couarraze
The authors compare three systems of single-screw extrusion (i.e., radial, dome, and axial) using binary formulations (i.e., microcrystalline cellulose, and active material) for their suitability for producing pellets of various formulations and under various spheronization conditions. Pellets were characterized by their size and shape, and by their structural and mechanical properties. The experimental design showed high variation between the three extrusion systems.
This article was also published in our US sister publication Pharmaceutical Technology and can be read
Articles in this issue
about 15 years ago
Optimising High-Potency Manufactureabout 15 years ago
The EMA And EU Expansionabout 15 years ago
The Rising Uptake Of Immediate Release And ODT Formulationsabout 15 years ago
Table Testing Techniquesabout 15 years ago
Celebration And Cinemaabout 15 years ago
Newsabout 15 years ago
The Influence Of Superdisintegrants On Immediate Releaseabout 15 years ago
The Single-Use Technology World Tourabout 15 years ago
Annex 11: Progress in EU Computer Systems Guidelinesabout 15 years ago
New Annex 11: Enabling Innovation