Genentech has announced that the waiting period under the Hart-Scott-Rodino Act has expired and it has completed the acquisition of US monoclonal antibody specialist Tanox.
Genentech has announced that the waiting period under the Hart-Scott-Rodino Act has expired and it has completed the acquisition of US monoclonal antibody specialist Tanox. Shareholders of Tanox approved the merger agreement in January this year.
Under the terms of the agreement, originally announced by the companies in November last year, Tanox stockholders are entitled to receive $20 in cash per share of common stock held at the closing, for a total cash value of approximately $919 million. These funds are being provided from Genentech's cash on hand. As a result of the acquisition, shares of Tanox common stock are no longer being traded on the NASDAQ Global Market.
"We are pleased with the closing of this important transaction which will provide us with improved profitability on Xolair, our FDA-approved anti-IgE monoclonal antibody for patients with moderate-to-severe allergic asthma," said David Ebersman, executive vice president and chief financial officer. "We will continue to work with our collaborator, Novartis to advance potential new indications and formulations of Xolair. We thank the Tanox employees, executive team and board of directors for their commitment to develop novel therapies for patients, and their efforts and dedication during the transition." The three-way collaboration between Genentech, Tanox and Novartis on the development and commercialization of Xolair (Omalizumab) began in 1996. The closing of the acquisition allows Genentech to eliminate the royalty on sales of the drug, which it previously paid to Tanox, and obtains Novartis' profit share and royalty payments to Tanox.
Understanding the Variability in Bioburden Test Results in Biomanufacturing
May 7th 2025This article explores the impact of test volume, microbial distribution, and dilution errors on bioburden testing variability. It presents statistical approaches to estimate percentage error and discusses strategies to optimize microbial enumeration techniques in biopharmaceutical quality control.
Trump Directs FDA, EPA to Reduce Regulatory Barriers to Domestic Pharma Manufacturing
May 7th 2025The White House is instructing FDA to increase fees for and inspections of foreign drug manufacturing plants and reduce the time required to approve such sites that will be newly constructed in the US.
Drug Solutions Podcast: A Closer Look at mRNA in Oncology and Vaccines
April 30th 2024In this episode fo the Drug Solutions Podcast, etherna’s vice-president of Technology and Innovation, Stefaan De Koker, discusses the merits and challenges of using mRNA as the foundation for therapeutics in oncology as well as for vaccines.