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Pharmaceutical Technology

Pharmaceutical Technology, October 2022
Volume46
Issue 10
Pages: 12

Inorganic DNA Replication Enzyme

The new inorganic pyrophosphate from Canvax is intended for use in RNA IVT reactions.

Canvax Inorganic Pyrophosphotate

Canvax Inorganic Pyrophosphotate

Canvax’s new inorganic pyrophosphatase is a DNA replication enhancer with ≥ 95% purity and has an enhanced capacity for increasing RNA yield in in-vitro transcription (IVT) reactions. The enzyme, which is isolated from Escherichia coli, has demonstrated stability below 80ºF, and is free of endonucleases, exonucleases, and RNAases.

The enzyme is intended for use in RNA IVT reactions, as it is designed to reduce the inhibitory effects of protein-protein interactions. In addition, it is suitable for use in messenger RNA-based vaccine manufacturing, RNA labeling, and enhancement of DNA replication.

Canvax

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