Lump Breaker Reduces Powder Agglomerates
The hygienic Gericke Nibbler can be used in pharma manufacturing.
Image courtesy of Gericke
The Nibbler line of lump breakers from process equipment manufacturer Gericke USA is now offered in a hygienic design to comply with FDA requirements. The hygienic lump breakers use a shaft assembly that allows the entire basket, screen, and front end to be removed and fully accessed for complete cleaning, inspections, and maintenance. The deagglomerators include woven wire screens in 316 stainless steel, continuously welded seams throughout, and polished internal surfaces.
The equipment reduces agglomerates, granules, and lumps down to 1 mm using attrition milling with a low speed, high-torque, rotating paddle assembly that cuts the material without damaging the product or generating excessive fine particles. A choice of screen sizes ensures the powders meet the required particle size. The equipment is available in seven standard models and may also be custom engineered.
Source: Gericke
Drug Solutions Podcast: Novel Drug Delivery Approaches: Refining AAV Vector Deliveries
May 30th 2025In this podcast episode, we discuss novel approaches to drug delivery, specifically regarding adeno-associated virus (AAV) vectors, as viewed by two industry experts who recently exhibited at the annual ASGCT meeting.
Transformations in Drug Development for Cell and Gene Therapies
March 28th 2025As a recognized leader in immunophenotyping for clinical trials, Kevin Lang from PPD discusses how spectral flow cytometry is transforming drug development, particularly in cell and gene therapies like CAR-T. He also dives into his award-winning research, including his 2024 WRIB Poster Award-winning work, and his insights from presenting at AAPS PharmSci360.
