Energy-Recovery System Saves Costs In Hot-Water Shower Sterilizers
Schoeller-Bleckmann Medizintechnik (SBM), a Bosch Packaging Technology company, developed an energy-saving concept that reduces costs for both heating and cooling.
Schoeller-Bleckmann Medizintechnik (SBM), a Bosch Packaging Technology company, developed an energy-saving concept that reduces both heating and cooling energy. The system works with hot-water shower sterilizers from SBM and also with sterilizers from third-party providers.
SBM's hot-water shower sterilizers are designed to sterilize liquids in completely sealed containers. The advantage of this process is short overall cycle times suited for products that are temperature-sensitive. An individual adjustable counter-pressure prevents the container from breaking or distorting during the entire cycle.
The self-contained, independent system consists of a multilayer storage tank, which is divided into several temperature zones and piped to the sterilizer via a heat exchanger. The water temperature in the permanently filled storage tank increases from bottom to top. Separation planes prevent the temperature zones from mixing too quickly. The stored energy is used for both heating and cooling of the sterilizer.
The water temperature of the sterilization phase is usually 121 °C. During cooling, the hot process water flows through the heat exchanger, where it is cooled by cold water from the storage tank. The water in the storage tank thereby absorbs energy from the sterilizer and heats up again. By using existing cold water from the multilayer storage, manufacturers can reduce the amount of additional, costly cooling medium. An intelligent control system enables the energy to be stored in the storage tank’s different temperature zones. After the sterilizer has been reloaded, the energy in the multilayer storage can be re-used to heat the process water to 121 °C.
A continuous repetition of these process steps reduces the required amounts of heating and cooling media. As a result, up to 40% of the initial heating energy can be saved. An additional heating exchanger integrated in the storage tank can save up to 60% of cooling energy.
Source: Bosch Packaging Technology
Ushering in Industry 4.0 with the IDMO Model to Solve the CGT Manufacturing Bottleneck
May 28th 2025Global scale-up requires developing replicable processes that work the same no matter where they are performed. This can be accomplished with smart factories that utilize fully automated manufacturing platforms.
Transformations in Drug Development for Cell and Gene Therapies
March 28th 2025As a recognized leader in immunophenotyping for clinical trials, Kevin Lang from PPD discusses how spectral flow cytometry is transforming drug development, particularly in cell and gene therapies like CAR-T. He also dives into his award-winning research, including his 2024 WRIB Poster Award-winning work, and his insights from presenting at AAPS PharmSci360.
Advancing Clinical Trials with Spectral Flow Cytometry: A Conversation with Kevin Lang
March 28th 2025As a recognized leader in immunophenotyping for clinical trials, Kevin Lang from PPD discusses how spectral flow cytometry is transforming drug development, particularly in cell and gene therapies like CAR-T. He also dives into his award-winning research, including his 2024 WRIB Poster Award-winning work, and his insights from presenting at AAPS PharmSci360.
Photometer Calibration: Calibration Error Due to Errors in Gravimetric Standard of Measurement
May 28th 2025This technical note explores the sources of error in gravimetric measurements used for aerosol photometer calibration, emphasizing the impact of discrepancies in aerosol properties, temporal instability, and flawed experimental procedures. It supports the two-point calibration practice to minimize errors, particularly at lower concentrations, and recommends measures such as improved aerosol systems and automation to enhance calibration accuracy. The findings aim to ensure reliable photometer performance for critical applications.
Photometer Calibration: The Case for Two-Point Calibration and Multi-Point Verification
May 28th 2025This technical note discusses the rationale for using two-point calibration and multi-point verification in the calibration of aerosol photometers. It explains the theoretical basis for the linear relationship between photometric response and aerosol mass concentration, highlights practical challenges with multi-point calibration, and advocates for two-point calibration to minimize errors. The combination of two-point calibration and multi-point verification ensures the accuracy and performance of the photometer in critical applications.
