Advances in Hot-Melt Extrusion Manufacturing, an Interview with Leistritz Extrusion

Hot-melt extrusion using twin-screw extruders is a continuous pharmaceutical manufacturing process that is being used to produce solid-dosage formulations. Twin-screw extrusion is a proven and well-understood manufacturing technology that has been used for 50 years in the plastics and food industries, and has been embraced by the pharmaceutical industry in the past decade. Charlie Martin, president of Leistritz Extrusion, speaks with Pharmaceutical Technology about the use of twin-screw extrusion in pharmaceutical processing today.