Ashland Announces Klucel xtend HPC Matrix Former

Ashland announced the introduction of Klucel xtend hydroxypropyl cellulose (HPC) controlled release matrix former on Oct. 3, 2022. It is designed to deliver process versatility and release profile efficiency.

According to a company press release, Klucel xtend HPC has been shown to match the release profile of widely used Hypromellose controlled-release formulations at half the polymer concentration. Prior to this product launch, Ashland claims that there were limited options for managing the release profile of controlled release formulations, especially high dose.

The reduced polymer concentration offers the possibility of smaller pills or higher dosage, presenting an option for easier tablet swallowability or a reduction in the number of tablets required for frequent medication. According to the release, this feature is intended to improve patient compliance with drug regimens.