Breakthrough in purification
Shimadzu’s new ASAPrep for RPC (“Automated Scale-up from Analytical to Preparative conditions for Reversed Phase Purification”) predicts success and failure of purification automatically and determines an optimal preparative condition.
The quality of purification processes in, e.g. medicinal chemistry, has been highly dependent on the chromatographers’ skill. Large pharmaceutical companies are capable of synthesizing hundreds of new compounds per day, but they cannot provide high purity compounds in sufficient amounts for High Throughput Screening (HTS), nor does the speed of purification match NCE (New Chemical Entities) synthesis.
Shimadzu’s new ASAPrep for RPC (“Automated Scale-up from Analytical to Preparative conditions for Reversed Phase Purification”) predicts success and failure of purification automatically and determines an optimal preparative condition. Based on an algorithm, the preparative method is created automatically, and users save time while increasing throughput. The algorithm calculates optimal initial organic mobile phase concentration in preparative scale using the retention time acquired by LC-PDA-MS measurement and judging of the difference between success and failure of purification.
ASAPrep for RPC runs on an LCMS-2010 single quadrupole system in analytical and preparative mode.
For more information please visit www.shimadzu.eu
Why is the PDA Pharmaceutical Microbiology Conference the Hottest Ticket in the Industry?
October 10th 2024Get a glimpse of the power and popularity behind the PDA Pharmaceutical Microbiology Conference from two planning committee members, Julia Marre, PhD (Associate Director, Scientific and Regulatory Affairs at Pocket Naloxone Corp) and Dawn Watson (Executive Director, Global Micro Quality and Sterility Assurance at Merck). This candid conversation reveals why this industry event is so influential…and always sold out! The speakers discuss what makes the PDA Pharmaceutical Microbiology Conference so vital to industry professionals, as well as how to become a part of this dynamic professional community.
